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Genetic Control of Variable and Constant Regions of Immunoglobulin Heavy Chains
Nature New Biology, 1971IMMUNOGLOBULIN polypeptide chains consist of two well defined regions designated the “variable region” and the “constant region”. Whereas great diversity exists in amino-acid sequences of variable regions, the constant regions of a given subclass of heavy chains (CH)* are essentially invariant in sequence1, 2.
R G, Mage +2 more
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Heating of immunoglobulins for immunoblot analysis destroys variable region antigenicity
Journal of Immunological Methods, 1986The antigenicity of rabbit immunoglobulin heavy chain variable region allotypes was examined by immunoblotting after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The standard method of sample preparation resulted in a total loss of immunoreactivity with anti-allotype antibody due to heating of the samples prior to their electrophoresis ...
V H, Van Cleave, D W, Metzger
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Association of variable and constant regions of immunoglobulin heavy chains
Immunochemistry, 1972J R, Pink +3 more
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Molecular genetics of immunoglobulin variable regions
1990M.J. SIMS, M.J. TAUSSIG
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The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
Journal of Experimental Medicine, 1998Fumihiko Matsuda +2 more
exaly
Organization and evolution of variable region genes of the human immunoglobulin heavy chain
Journal of Molecular Biology, 1986Tatsuo Kinashi +2 more
exaly
[Variable region of immunoglobulin, genes and their expressions].
Nihon rinsho. Japanese journal of clinical medicine, 1977S, Migita, S, Sakai
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