Results 41 to 50 of about 214,734 (307)

Alterations in immunoglobulin levels in uninfected children born to HIV infected women [PDF]

, 2008
Background Immunoglobulin levels are known to be elevated in HIV infected children. However, little is known about the effect of maternal HIV infection and the maternal altered immune system on immunoglobulin levels in uninfected children. As few data
Bunders, M., Kuijpers, T., Newell, M-L, Pembrey, L.   +3 more
core  

A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence [PDF]

, 1977
Rabbit antibodies against actin and tubulin were used in an indirect immunofluorescence study of the structure of the mitotic spindle of PtK1 cells after lysis under conditions that preserve anaphase chromosome movement. During early prophase there is no
Cande, W. Zacheus, Lazarides, Elias, McIntosh, J. Richard   +2 more
core   +5 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Pattern of serum immunoglobulins and free light chain levels among patients diagnosed with multiple myeloma in Southeast Nigeria

International Journal of Medicine and Health Development, 2023
Background: Abnormal plasma cells in multiple myeloma produce excessive amounts of immunoglobulins and free light chains, of which certain patterns predict patient survival.
Ifeyinwa D Nnakenyi, Anazoeze J Madu, Ifeoma C Ajuba, Sunday Ocheni, Gladys U Ilechukwu, Nnenna Ogbodo, Oji A Nnachi   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Correlation between total IgE level and asthma symptom severity in hospitalized children

Journal of Allergy and Clinical Immunology: Global
Background: Status asthmaticus is a common reason for hospitalization and pediatric intensive care unit (PICU) admission among children. While previous studies have demonstrated a correlation between elevated IgE levels and asthma severity in outpatient ...
Tasmia Rezwan, MD, Michelle Perez, MD, Sarah Jacobs, Justina Shafik, William B. Mitchell, MD, Laura A. Conrad, DO, Sara H. Soshnick, DO   +6 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection

Frontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix.
Mohamad N. Ali, Mohamad N. Ali, Gopinath Kasetty, Malin Elvén, Saud Alyafei, Sandra Jovic, Arne Egesten, Heiko Herwald, Artur Schmidtchen, Artur Schmidtchen, Artur Schmidtchen, Praveen Papareddy, Praveen Papareddy   +12 more
doaj   +1 more source

Structure-function relations in phosphorylcholine-binding mouse myeloma proteins [PDF]

, 1977
The binding site interactions between the phosphorylcholine (phosphocholine)-binding mouse myeloma proteins TEPC 15, W3207, McPC 603, MOPC 167, and MOPC 511 and the isotopically substituted hapten phosphoryl-[methyl-13C]choline have been investigated ...
Goetze, Andrew M., Richards, John H.
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Gestational Pemphigoid—From Molecular Mechanisms to Clinical Outcomes: A Case Report and Review of Literature

Life
Gestational pemphigoid is a rare, autoimmune, subepidermal bullous disease with an incidence of 1 in 50,000 pregnancies, displaying itself through pruritic erythema and urticarial papules and plaques that evolve into tense bullae.
Miruna Ioana Cristescu, Cristina Violeta Tutunaru, Anca Panaitescu, Vlad Mihai Voiculescu   +3 more
doaj   +1 more source