Results 41 to 50 of about 157,523 (294)

Gestational Pemphigoid—From Molecular Mechanisms to Clinical Outcomes: A Case Report and Review of Literature

open access: yesLife
Gestational pemphigoid is a rare, autoimmune, subepidermal bullous disease with an incidence of 1 in 50,000 pregnancies, displaying itself through pruritic erythema and urticarial papules and plaques that evolve into tense bullae.
Miruna Ioana Cristescu   +3 more
doaj   +1 more source

Evaluation of Hypogammaglobulinemia in Chronic Lymphocytic Leukemia Patients and Its Relation to Poor Prognostic Factors

open access: yesHaseki Tıp Bülteni, 2018
Aim:Chronic lymphocytic leukemia (CLL) is a heterogenous disease with variable clinical course. Rai staging system is used for at least 40 years to predict prognosis and need for treatment but more prognostic factors are needed.
Mesut Ayer   +4 more
doaj   +1 more source

Impact of Binge Alcohol Intoxication on the Humoral Immune Response during Burkholderia spp. Infections

open access: yesMicroorganisms, 2019
Burkholderia pseudomallei, the causative agent of melioidosis can occur in healthy humans, yet binge alcohol use is progressively being recognized as a major risk factor.
Ryan M. Moreno   +2 more
doaj   +1 more source

Primary Cutaneous Amyloidosis: A Clinical, Histopathological and Immunofluorescence Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Primary Localized Cutaneous Amyloidosis (PLCA) is a relatively rare chronic condition characterized by amyloid deposition in dermis without associated deposits in internal organs.
Krati Mehrotra   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Human body resistance dynamics in the post-covid period

open access: yesИнфекция и иммунитет
The issue of the state of specific and nonspecific resistance in the post-COVID period and the possible consequences of COVID-19 remains poorly understood.
Ekaterina V. Zhdanova   +2 more
doaj   +1 more source

Late diagnosis of agammaglobulinemia in an 8-year-old boy

open access: yesPediatria i Medycyna Rodzinna, 2016
Chromosome X-linked Bruton agammaglobulinemia is classified as a primary immunodeficiency disorder. It is a genetic condition associated with a mutation in the BTK gene encoding tyrosine kinase.
Małgorzata Sopińska   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mass spectrometry-based analysis of rheumatoid factor

open access: yesFrontiers in Immunology
IntroductionRheumatoid factor (RF) are autoantibodies that are found in approximately two thirds of patients with rheumatoid arthritis, a chronic autoimmune disease characterized by potentially destructive inflammation of the joints.
Jonas De Leeuw   +19 more
doaj   +1 more source

Thrombocytopenia in the Course of COVID-19 Infection

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2020
We report three cases of severe thrombocytopenia during COVID-19 infection associated with either cutaneous purpura or mucosal bleeding. The initial investigations ruled out other causes of thrombocytopenia.
Noel Lorenzo-Villalba   +7 more
doaj   +1 more source

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