Results 51 to 60 of about 464,654 (331)

Correlation between total IgE level and asthma symptom severity in hospitalized children

Journal of Allergy and Clinical Immunology: Global
Background: Status asthmaticus is a common reason for hospitalization and pediatric intensive care unit (PICU) admission among children. While previous studies have demonstrated a correlation between elevated IgE levels and asthma severity in outpatient ...
Tasmia Rezwan, MD, Michelle Perez, MD, Sarah Jacobs, Justina Shafik, William B. Mitchell, MD, Laura A. Conrad, DO, Sara H. Soshnick, DO   +6 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection

Frontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix.
Mohamad N. Ali, Mohamad N. Ali, Gopinath Kasetty, Malin Elvén, Saud Alyafei, Sandra Jovic, Arne Egesten, Heiko Herwald, Artur Schmidtchen, Artur Schmidtchen, Artur Schmidtchen, Praveen Papareddy, Praveen Papareddy   +12 more
doaj   +1 more source

A Novel Immunoglobulin-Immunoglobulin Interaction in Autoimmunity

PLoS ONE, 2008
Well over six decades since its first description, the Rheumatoid Factor (RF)-autoantibodies recognizing Fc (constant) portion of IgG through their own Fab (antigen binding variable segments)-is believed to have come of age. Autoimmune pancreatitis is a unique form of pancreatitis, biologically characterized by an elevated serum IgG4 concentration ...
Shigeyuki Kawa, Kei Kitahara, Hideaki Hamano, Yayoi Ozaki, Norikazu Arakura, Kaname Yoshizawa, Takeji Umemura, Masao Ota, Sadaaki Mizoguchi, Yasunori Shimozuru, Seiamak Bahram   +10 more
openaire   +4 more sources

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Gestational Pemphigoid—From Molecular Mechanisms to Clinical Outcomes: A Case Report and Review of Literature

Life
Gestational pemphigoid is a rare, autoimmune, subepidermal bullous disease with an incidence of 1 in 50,000 pregnancies, displaying itself through pruritic erythema and urticarial papules and plaques that evolve into tense bullae.
Miruna Ioana Cristescu, Cristina Violeta Tutunaru, Anca Panaitescu, Vlad Mihai Voiculescu   +3 more
doaj   +1 more source

Evaluation of Hypogammaglobulinemia in Chronic Lymphocytic Leukemia Patients and Its Relation to Poor Prognostic Factors

Haseki Tıp Bülteni, 2018
Aim:Chronic lymphocytic leukemia (CLL) is a heterogenous disease with variable clinical course. Rai staging system is used for at least 40 years to predict prognosis and need for treatment but more prognostic factors are needed.
Mesut Ayer, Çağan M. Akay, Fatma Aylin Ayer, Deniz Özmen, Tayfun Elibol   +4 more
doaj   +1 more source

Impact of Binge Alcohol Intoxication on the Humoral Immune Response during Burkholderia spp. Infections

Microorganisms, 2019
Burkholderia pseudomallei, the causative agent of melioidosis can occur in healthy humans, yet binge alcohol use is progressively being recognized as a major risk factor.
Ryan M. Moreno, Victor Jimenez, Fernando P. Monroy   +2 more
doaj   +1 more source

Primary Cutaneous Amyloidosis: A Clinical, Histopathological and Immunofluorescence Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Primary Localized Cutaneous Amyloidosis (PLCA) is a relatively rare chronic condition characterized by amyloid deposition in dermis without associated deposits in internal organs.
Krati Mehrotra, Rupali Dewan, Jagannath V Kumar, Abhinav Dewan   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Human body resistance dynamics in the post-covid period

Инфекция и иммунитет
The issue of the state of specific and nonspecific resistance in the post-COVID period and the possible consequences of COVID-19 remains poorly understood.
Ekaterina V. Zhdanova, E. V. Rubtsova, E. G. Kostolomova   +2 more
doaj   +1 more source