Results 61 to 70 of about 464,654 (331)
Late diagnosis of agammaglobulinemia in an 8-year-old boy
Pediatria i Medycyna Rodzinna, 2016 Chromosome X-linked Bruton agammaglobulinemia is classified as a primary immunodeficiency disorder. It is a genetic condition associated with a mutation in the BTK gene encoding tyrosine kinase.
Małgorzata Sopińska +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mass spectrometry-based analysis of rheumatoid factor
Frontiers in ImmunologyIntroductionRheumatoid factor (RF) are autoantibodies that are found in approximately two thirds of patients with rheumatoid arthritis, a chronic autoimmune disease characterized by potentially destructive inflammation of the joints.
Jonas De Leeuw +19 more
doaj +1 more source
Thrombocytopenia in the Course of COVID-19 Infection
European Journal of Case Reports in Internal Medicine, 2020 We report three cases of severe thrombocytopenia during COVID-19 infection associated with either cutaneous purpura or mucosal bleeding. The initial investigations ruled out other causes of thrombocytopenia.
Noel Lorenzo-Villalba +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Clinical Case Reports, 2017 Key Clinical Message A 71‐year‐old female patient with no major history of infection had presented with recurrent chronic purulent sinusitis over the past 3 years.
Gérard Dine +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Effect of a combined clostridial vaccine on cytokine and immunoglobulin levels in lambs
Revista CientíficaInfections caused by clostridial agents are difficult to treat and have a high mortality rate. This study aimed to determine the effects of the recommended dose of a commercial clostridial vaccine on serum levels of TNF–α, IL–1β, IL–6, and IL–10, and ...
Rahmi Canbar +3 more
doaj +1 more source
Immunoglobulin Treatment in Severe Ovarian Hyperstimulation Syndrome
European Journal of Case Reports in Internal Medicine, 2019 A 32-year-old woman undergoing an in vitro fertilization program was admitted to our hospital with the diagnosis of severe ovarian hyperstimulation syndrome (OHSS). Transvaginal ultrasonography showed two gestational sacs.
Gemma Grau +4 more
doaj +1 more source
An Atypical Immunoglobulin [PDF]
Blood, 1968 Abstract A protein of the Ig G family has been isolated from the serum of a patient with a tentative diagnosis of a plasma cell neoplasm. The protein has a lower sedimentation constant (5.4) and a lower molecular weight (125,000) than normal immunoglobulins of the G family.
A F, Lewis +4 more
openaire +2 more sources