Results 71 to 80 of about 214,734 (307)

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
André A., S., André K., S., Barbora Dvořánková, Bergmann J., M., Cheb Y.-Y., S.-J., Dam T.K., Demetter O., P., Dvoránková J., B., Engelhardt H.-J., R., Eva Sykova, Fischer H., C., Fritz A., P., Hans-Joachim Gabius, Herbert Kaltner, Hung C.W., Jana Uhrova, Jones D.L., Jones G.E., Jones G.E., Karel Smetana, Jr., Kim Y.-B., H.-W., Kojima S., S., Lacina H., L., Lacina J., L., Lataillade T., J.-J., Legendre N., H., Lensch A., M., Lu J., Z.-H., Lukas Lacina, Miller S.N., Nagy I., N., Nakachi Y., K., Nogales-Gonzalés A., A., O’Donoghue J., K., Pavol Szabo, Pei S., Z., Peter Gal, Sabine André, Sanchez-Ruderisch C., H., Sanchez-Ruderisch S., H., Sansone S., F., Seyrek H., K., Smetana B., K., Smetana L., K., Smetana Z., K., Tomas Zima, Uchida K., K., von Reitzenstein J., C.   +47 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Preparation of diagnostic ELISA kits for detection of camelpox virus

Journal of Veterinary Medical Research, 2005
Peroxidase labeled immunoglobulins to camelpox virus (CPV) were prepared for use in various techniques of ELISA. Ten rabbits and three goats were inoculated with a mixture of camelpox virusand Freund’s adjuvant.
E. A. Aboul Soud, Magda, M. Sayed, A. A. Badawi, M. M. Taha, Elham A. El-Ebiary, A. M. Daoud   +5 more
doaj  

Lactoferrin and immunoglobulin content in camel milk from bactrian, dromedary and hybrids in Kazakhstan [PDF]

, 2008
Milk of Camelidae is well-known for there health effects on human. This effect is partially attributed to their antibacterial properties. These properties could be linked to some substances, like proteins, lipids and vitamins.
Faye, Bernard, Konuspayeva, Gaukhar, Levieux, Didier, Loiseau, Gérard   +3 more
core  

Bortezomib-containing multimodality treatment for antibody-mediated rejection with anti-HLA and anti-AT1R antibodies after kidney transplantation [PDF]

, 2017
For decades, the human leukocyte antigen (HLA) complex has been considered the primary target of antibody-mediated rejection (AMR), and treatment strategies have mainly focused on anti-HLA antibodies.
Favi, Evaldo, Iesari, Samuele, Lai, Quirino, Pisani, Francesco   +3 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The role of small intestine in pathogenesis of common variable immune deficiency [PDF]

Терапевтический архив, 2018
The article presents the results of examination of 32 patients with common variable immune deficiency (barn) with involvement in the pathological process of the digestive system. The features of the clinical picture, the content of immunoglobulins in the
L M Krums, A I Parfenov, R B Gudkova, S V Bykova, E A Sabelnikova   +4 more
doaj   +1 more source

Maternal and infant infections stimulate a rapid leukocyte response in breastmilk [PDF]

, 2013
Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and
Filgueira, L, Hartmann, P, Hassiotou, F, Hepworth, A, Lai, C, Metzger, P, Trengove, N   +6 more
core   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Neutralization Activity of Standard and Hyperimmune Intravenous Immunoglobulins Against Recently Circulating SARS-CoV-2 Variants

Vaccines
Our study demonstrates that IVIG lots manufactured in 2023–2024 contain neutralizing antibodies against circulating Omicron variants, including KP.3 and XEC.
Dongxiao Liu, Lorenza Bellusci, Hana Golding, Surender Khurana   +3 more
doaj   +1 more source