Results 121 to 130 of about 4,743 (216)

Navigating the immunosuppressive brain tumor microenvironment using spatial biology

open access: yesImmunoInformatics
With the application of spatial biology, the detection and identification of the diverse cell types present in the tumor microenvironment, including specific immune subsets, is possible at single cell resolution.
Samuel S. Widodo   +5 more
doaj  

Engineering a novel subunit vaccine against SARS-CoV-2 by exploring immunoinformatics approach

open access: gold, 2020
Bishajit Sarkar   +3 more
openalex   +1 more source

Transfer learning improves pMHC kinetic stability and immunogenicity predictions

open access: yesImmunoInformatics
The cellular immune response comprises several processes, with the most notable ones being the binding of the peptide to the Major Histocompability Complex (MHC), the peptide-MHC (pMHC) presentation to the surface of the cell, and the recognition of the ...
Romanos Fasoulis   +4 more
doaj  

In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection

open access: yesImmunoInformatics
CD8 T cell proper differentiation during antiviral responses relies on metabolic adaptations. Herein, we investigated global metabolic activity in single CD8 T cells along an in vivo response by estimating metabolic fluxes from single-cell RNA-sequencing
Christophe Arpin   +2 more
doaj  

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