Results 351 to 360 of about 840,473 (392)
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Alternative activation of macrophages: an immunologic functional perspective.
Annual Review of Immunology, 2009Macrophages are innate immune cells with well-established roles in the primary response to pathogens, but also in tissue homeostasis, coordination of the adaptive immune response, inflammation, resolution, and repair. These cells recognize danger signals
F. Martínez, L. Helming, S. Gordon
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Immunology and the immunological response in pregnancy
Best Practice & Research Clinical Obstetrics & Gynaecology, 2021The immune system in humans is a complex system capable of discriminating self from non-self, and mounting appropriate allogenic immune responses to protect themselves from foreign organisms. This system is made up of two arms of defense: the first one is a non-specific arm (innate), in which humans are born with and do not require antigenic ...
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Arthritis & Rheumatism, 2002
OBJECTIVE To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression.
R. Cervera +27 more
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OBJECTIVE To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression.
R. Cervera +27 more
semanticscholar +1 more source
Molecular Ecology, 2011
AbstractIn wild populations, individuals are regularly exposed to a wide range of pathogens. In this context, organisms must elicit and regulate effective immune responses to protect their health while avoiding immunopathology. However, most of our knowledge about the function and dynamics of immune responses comes from laboratory studies performed on ...
Simon A. Babayan, Amy B. Pedersen
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AbstractIn wild populations, individuals are regularly exposed to a wide range of pathogens. In this context, organisms must elicit and regulate effective immune responses to protect their health while avoiding immunopathology. However, most of our knowledge about the function and dynamics of immune responses comes from laboratory studies performed on ...
Simon A. Babayan, Amy B. Pedersen
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2019
Abstract The immunology chapter covers how HIV affects the immune system as whole. Mechanisms of chronic inflammation in HIV are discussed as well as pathogenesis of immune reconstitution inflammatory syndromes (IRIS). Immunologic effects of antiretroviral therapy and the role of persistent immune dysfunction during therapy on clinical ...
Dennis J. Hartigan-O’Connor +1 more
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Abstract The immunology chapter covers how HIV affects the immune system as whole. Mechanisms of chronic inflammation in HIV are discussed as well as pathogenesis of immune reconstitution inflammatory syndromes (IRIS). Immunologic effects of antiretroviral therapy and the role of persistent immune dysfunction during therapy on clinical ...
Dennis J. Hartigan-O’Connor +1 more
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Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.
Journal of Immunology, 1995The scid mutation was backcrossed ten generations onto the NOD/Lt strain background, resulting in an immunodeficient stock (NOD/LtSz-scid/scid) with multiple defects in adaptive as well as nonadaptive immunologic function.
L. Shultz +9 more
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Immunologic basis of antigen-induced airway hyperresponsiveness.
Annual Review of Immunology, 1999The incidence, morbidity, and mortality of asthma has increased worldwide over the last two decades. Asthma is a complex inflammatory disease of the lung characterized by variable airflow obstruction, airway hyperresponsiveness (AHR), and airway ...
M. Wills-Karp
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Nature Immunology, 2014
Asthma is a common disease that affects 300 million people worldwide. Given the large number of eosinophils in the airways of people with mild asthma, and verified by data from murine models, asthma was long considered the hallmark T helper type 2 (TH2) disease of the airways. It is now known that some asthmatic inflammation is neutrophilic, controlled
Bart N Lambrecht, Hamida Hammad
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Asthma is a common disease that affects 300 million people worldwide. Given the large number of eosinophils in the airways of people with mild asthma, and verified by data from murine models, asthma was long considered the hallmark T helper type 2 (TH2) disease of the airways. It is now known that some asthmatic inflammation is neutrophilic, controlled
Bart N Lambrecht, Hamida Hammad
openaire +4 more sources
The spectrum of vasculitis: clinical, pathologic, immunologic and therapeutic considerations.
Annals of Internal Medicine, 1978Vasculitis is a clinicopathologic process characterized by inflammation and necrosis of blood vessels. Certain disorders have vasculitis as the predominant and most obvious manifestation, whereas others have various degrees of vasculitis in association ...
A. Fauci, B. Haynes, P. Katz
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International Forum of Allergy & Rhinology, 2014
BackgroundKnowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies.MethodsThis review explains the current understanding of the basic immunology of the upper airways and the pathophysiology
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BackgroundKnowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies.MethodsThis review explains the current understanding of the basic immunology of the upper airways and the pathophysiology
openaire +2 more sources