Results 81 to 90 of about 821,023 (416)
Immunologic manifestations of autophagy.
Journal of Clinical Investigation, 2015 The broad immunologic roles of autophagy span innate and adaptive immunity and are often manifested in inflammatory diseases. The immune effects of autophagy partially overlap with its roles in metabolism and cytoplasmic quality control but typically ...
V. Deretic +5 more
semanticscholar +1 more source
eLife, 2019 Immunology and philosophy have a rich history of dialogue. Immunologists have long been influenced by ideas from philosophy, notably the concept of 'self', and many philosophers have explored the conceptual, theoretical and methodological foundations of immunology.
openaire +6 more sources
Cellular & Molecular Immunology, 2015 This editorial introduces several review articles focused on cytomegalovirus, including immune response to this virus, congenital cytomegalovirus infection, vaccines etc. All these articles are part of the special issue published in Cellular and Molecular Immunology.
openaire +4 more sources
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
Infections in the Era of Targeted Therapies: Mapping the Road Ahead
Frontiers in Medicine, 2020 Immunosuppressive treatment strategies for autoimmune diseases have changed drastically with the development of targeted therapies. While targeted therapies have changed the way we manage immune mediated diseases, their use has been attended by a variety
Leonard H. Calabrese +6 more
doaj +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
BMC Complementary and Alternative Medicine, 2019 Background We previously reported that tacrolimus (Tac) does not decrease T helper 17 cells (Th17) response in kidney transplantation. In this study, we evaluated whether Resveratrol (Resv) has immunosuppressive effects by decreasing Th17 responses in ...
Kyoung Chan Doh +4 more
doaj +1 more source
Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study. [PDF]
, 2012 Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood.
Boulle, Andrew +13 more
core +7 more sources
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells
Cell Reports, 2018 A balance between Th17 and regulatory T (Treg) cells is critical for immune homeostasis and tolerance. Our previous work has shown Serum- and glucocorticoid-induced kinase 1 (SGK1) is critical for the development and function of Th17 cells. Here, we show
Chuan Wu +6 more
doaj +1 more source