Results 61 to 70 of about 330,438 (316)
, 1990 Part I of this series appeared in the January 1990 issue. This two-part review addresses pharmacists' need for information about immunologic drug interactions.
Edward A. Hartshorn, John D. Grabenstein
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
ClinicoEconomics and Outcomes Research, 2023 Richard F Pollock,1 Andreas K Slættanes,2 Henrik Brandi,2 Tobias Sydendal Grand2 1Covalence Research Ltd, Harpenden, UK; 2ALK-Abelló A/S, Hørsholm, DenmarkCorrespondence: Andreas K Slættanes, ALK-Abelló A/S, Bøge Allé 1, Hørsholm, DK-2970, Denmark, Tel ...
Pollock RF +3 more
doaj
Potential effects of Linh Loc Son hard capsule – a Vietnamese herbal combination in immunodeficiency induced by cyclophosphamide on mice [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Traditional medicine and herbal extracts have long been recognized for their immunomodulatory effects, enhancing patient immune responses. The use of traditional medicine to target specific pathogens and support the immune system is increasingly
Binh Quoc Pham +7 more
doaj +1 more source
Infections in the Era of Targeted Therapies: Mapping the Road Ahead
Frontiers in Medicine, 2020 Immunosuppressive treatment strategies for autoimmune diseases have changed drastically with the development of targeted therapies. While targeted therapies have changed the way we manage immune mediated diseases, their use has been attended by a variety
Leonard H. Calabrese +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Cellular Immunology, 1979 Immunity to disease has long been recognized, but only during the late nineteenth century, thanks to Louis Pasteur, Robert Koch, Elie Metchnikoff and Paul Ehrlich, did immunology become a true science able to explain mechanisms and to develop preventive vaccines.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source