Results 51 to 60 of about 330,438 (316)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

In Vitro Analysis of the Proliferation of HaCaT Cells Stimulated by Pigments Used for Maxillofacial Prostheses

open access: yesJournal of Orofacial Sciences, 2019
Introduction: Although physical and mechanical properties are extremely important for the effectiveness of prosthetic treatment, materials used for facial rehabilitation should be biocompatible, as the maxillofacial prosthesis is in close contact with ...
Marcelo Coelho Goiato   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Immunologic failure risk assessment and management tool.

open access: yes, 2015
Immunologic failure risk assessment and management tool.
Susan Hattingh (737310)   +1 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Citotoxicidad del glifosato en células mononucleares de sangre periférica humana

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. El glifosato es un herbicida de amplio espectro, no selectivo, utilizado comúnmente en agricultura para eliminar malezas. Los estudios que han evaluado la toxicidad del glifosato en animales y en ambiente muestran que las formulaciones ...
Adriano Martínez   +2 more
doaj   +1 more source

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis

open access: yesNature Communications, 2021
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell ...
Thais G. Moreira   +18 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Labyrinthin: A distinct pan-adenocarcinoma diagnostic and immunotherapeutic tumor specific antigen

open access: yesHeliyon, 2022
Structural analysis and detection of optimal cell surface localization of labyrinthin, a pan-adenocarcinoma target, was studied with respect to adenocarcinoma specificity vs. normal and non-adenocarcinoma cells.
Michael Babich   +3 more
doaj   +1 more source

T Cells Immunology in the Immunological Diseases

open access: yesJournal of Immunology Research, 2014
Immunological diseases, with the morbidity keeping increased, have become a major threat to human mental and physical health. However, the pathogenesis of these diseases is extremely complicated and remains unclear. Recent advances in biology have introduced new technologies to study the underlying mechanisms that contribute to the development of ...
Xiuli Wu   +3 more
openaire   +3 more sources

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