Results 1 to 10 of about 936,977 (378)

Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression. [PDF]

PLoS ONE, 2017
The role of natural killer (NK) cell function in HIV disease especially in the setting of long-term antiretroviral therapy (ART) and viral suppression is not fully understood.
Zhenwu Luo, Zhen Li, Lisa Martin, Zhiliang Hu, Hao Wu, Zhuang Wan, Michael Kilby, Sonya L Heath, Lei Huang, Wei Jiang   +9 more
doaj   +2 more sources

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

Journal for ImmunoTherapy of Cancer, 2022
Background Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial ...
Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn   +14 more
doaj   +2 more sources

Cytoskeletal stabilization of inhibitory interactions in immunologic synapses of mature human dendritic cells with natural killer cells [PDF]

Blood, 2011
Human mature dendritic cells (DCs) can efficiently stimulate natural killer (NK)-cell responses without being targeted by their cytotoxicity. To understand this important regulatory crosstalk, we characterized the development of the immunologic synapse ...
Barreira da Silva, Rosa, Graf, C, Münz, C   +2 more
core   +2 more sources

Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation [PDF]

Frontiers in Immunology
IntroductionXenotransplantation using genetically modified pigs is a promising solution to organ shortages, particularly for highly sensitized patients with broad anti-HLA sensitization who lack compatible allografts.
Sang-Ik Cho, Ji-Jing Yan, Beom Seok Kim, Beom Seok Kim, Nayoung Ko, Joohyun Shim, Hyunil Kim, Eun-Jee Oh, Eun-Jee Oh   +8 more
doaj   +2 more sources

Immunologic Cytotoxicity in Alopecia Areata: Apoptosis of Dermal Papilla Cells in Alopecia Areata

Journal of Investigative Dermatology, 1995
David A. Nortis, Richard C. Duke, Kyu Kwang Whang, Marjorie H. Middleton   +3 more
openalex   +2 more sources

Wiskott–Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses

Proceedings of the National Academy of Sciences of the United States of America, 2002
Jordan S. Orange, Narayanaswamy Ramesh, Eileen Remold‐O’Donnell, Yoji Sasahara, Louise A. Koopman, Michael Byrne, Francisco A. Bonilla, Fred S. Rosen, Raif S. Geha, Jack L. Strominger   +9 more
openalex   +2 more sources

Single‐cell profiling identifies distinct hormonal, immunologic, and inflammatory signatures of endometriosis‐constituting cells

Journal of Pathology, 2023
Endometriosis consists of ectopic endometrial epithelial cells (EEECs) and ectopic endometrial stromal cells (EESCs) mixed with heterogeneous stromal cells.
Sun Shin, Youn-Jee Chung, Seong Won Moon, Eun Ji Choi, Mee-Ran Kim, Yeun-Jun Chung, S. Lee   +6 more
semanticscholar   +1 more source

Anti-inflammatory effect of amalgam on periapical lesion cells in culture [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Amalgam has been used for years in dentistry, but the controversy on its adverse effects, both on local oral/dental tissues and systemic health, still exists.
Eraković Mile, Duka Miloš, Bekić Marina, Milanović Marijana, Tomić Sergej, Vučević Dragana, Čolić Miodrag   +6 more
doaj   +1 more source

Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?

Brazilian Journal of Nephrology, 2021
Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric
Jamile Abud, Bruna Brasil Dal Pupo, Cynthia da Silva, Elizete Keitel, Valter Duro Garcia, Roberto Ceratti Manfro, Jorge Neumann   +6 more
doaj   +2 more sources

Immunologic difference between hypersensitivity to mosquito bite and hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection. [PDF]

PLoS ONE, 2013
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of Chronic Active Epstein-Barr Virus infection (CAEBV), may progress to HLH.
Wen-I Lee, Jainn-Jim Lin, Meng-Ying Hsieh, Syh-Jae Lin, Tang-Her Jaing, Shih-Hsiang Chen, Iou-Jih Hung, Chao-Ping Yang, Chin-Jung Chen, Yhu-Chering Huang, Shin-Pai Li, Jing-Long Huang   +11 more
doaj   +1 more source