Results 111 to 120 of about 880,908 (352)

Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development

Experimental Biology and Medicine, 2011
Immunogenic T-cell epitopes have a central role in the cellular immunity against pathogens and tumors. However, in the early stage of cellular immunity studies, it was complicated and time-consuming to identify and characterize T-cell epitopes. Currently, the epitope screening is experiencing renewed enthusiasm due to advances in novel techniques and ...
Shihong Zhang, Jun Liu, Beiwen Zheng, Shuguang Tan, George F. Gao   +4 more
openaire   +3 more sources

Ultra‐Effective Light‐Activated Antibacterial Activity via Carboxyl Functionalized Graphene Quantum Dots and Films

Advanced Functional Materials, EarlyView.
Carboxyl‐functionalized graphene quantum dots (cGQDs) exhibit high singlet oxygen quantum yield due to strong spin–orbit coupling. cGQDs achieve minimum bactericidal concentration of only 0.4 µg mL−1 against S. aureus under low‐intensity illumination.
Muhammad Hassnain, Laure S. van Hofwegen, Humeyra Nur Kaleli, Temirlan Kubanaliev, Zafer Eroglu, Asim Onal, Payal P. S. Balraadjsing, Onder Metin, Fahri Alkan, Sebastian A. J. Zaat, Sedat Nizamoglu   +10 more
wiley   +1 more source

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

OncoImmunology, 2019
Background: Intravesical bacillus Calmette-Guérin (BCG) is the gold standard immunologic agent for treating patients with high-grade non-muscle invasive bladder cancer (NMIBC).
Niannian Ji, Neelam Mukherjee, Edwin E. Morales, Maggie E. Tomasini, Vincent Hurez, Tyler J. Curiel, Getahun Abate, Dan F. Hoft, Xiang-Ru Zhao, Jon Gelfond, Sourindra Maiti, Laurence J.N. Cooper, Robert S. Svatek   +12 more
doaj   +1 more source

Tumor-Specific Antibody, Cetuximab, Enhances the In Situ Vaccine Effect of Radiation in Immunologically Cold Head and Neck Squamous Cell Carcinoma

Frontiers in Immunology, 2020
In head and neck squamous cell carcinoma (HNSCC) tumors that over-expresses huEGFR, the anti-EGFR antibody, cetuximab, antagonizes tumor cell viability and sensitizes to radiation therapy.
Won Jong Jin, Amy K. Erbe, Ciara N. Schwarz, Abigail A. Jaquish, Bryce R. Anderson, Raghava N. Sriramaneni, Justin C. Jagodinsky, Amber M. Bates, Paul A. Clark, Trang Le, Keng-Hsueh Lan, Yi Chen, KyungMann Kim, Zachary S. Morris   +13 more
doaj   +1 more source

Modelling Immunological Memory [PDF]

In Silico Immunology, 83-108, 2006, 2010
Accurate immunological models offer the possibility of performing highthroughput experiments in silico that can predict, or at least suggest, in vivo phenomena. In this chapter, we compare various models of immunological memory. We first validate an experimental immunological simulator, developed by the authors, by simulating several theories of ...
arxiv  

Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth [PDF]

arXiv, 2020
Prostate cancer can be lethal in advanced stages, for which chemotherapy may become the only viable therapeutic option. While there is no clear clinical management strategy fitting all patients, cytotoxic chemotherapy with docetaxel is currently regarded as the gold standard.
arxiv  

Data from Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression [PDF]

, 2023
A.K.M. Ghulam Muhammad, Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, David Foulad, Yohei Mineharu, Kurt M. Kroeger, Katherine A. Treuer, W. Stephen Nichols, Nicholas Sanderson, Jieping Yang, Maksim Khayznikov, Nico van Rooijen, Pedro R. Löwenstein, María G. Castro   +14 more
openalex   +1 more source

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

An Effective Membrane Model of the Immunological Synapse [PDF]

, 2003
The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different ...
arxiv   +1 more source

Supplementary Data from Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression [PDF]

, 2023
A.K.M. Ghulam Muhammad, Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, David Foulad, Yohei Mineharu, Kurt M. Kroeger, Katherine A. Treuer, W. Stephen Nichols, Nicholas Sanderson, Jieping Yang, Maksim Khayznikov, Nico van Rooijen, Pedro R. Löwenstein, María G. Castro   +14 more
openalex   +1 more source