Results 111 to 120 of about 30,728 (210)

Paclitaxel Modulates the Proliferation and Differentiation of THP-1 Cells Exposed to Inactivated SARS-CoV-2 Virus

Revista Brasileira de Cancerologia
Introduction: Cancer patients were considered a high-risk group for COVID-19. Studies indicate that certain types of cancer, as breast cancer, may exhibit distinct immunological responses.
Everaldo Hertz, Bárbara Osmarin Turra, Nathália Cardoso de Afonso Bonotto, Fernanda dos Santos Trombini, João Arthur Bittencourt Zimmermann, Cibele Ferreira Teixeira, Verônica Farina Azzolin, Ivo Emilio da Cruz Jung, Ivana Beatrice Mânica da Cruz, Fernanda Barbisan   +9 more
doaj   +1 more source

Identification of immunological genes important for cytotoxicity

, 2019
Natural Killer (NK) cells and Cytotoxic T lymphocytes (CTLs) are essential to defend the body against foreign or transformed cells. An understanding of the mechanism of their cytotoxicity can result in the generation of genetically modified cells with higher cytotoxicity and to identify drug-targets that increase cytotoxicity.
openaire   +1 more source

The Influence of Indisulam on Human Immune Effector Cells: Is a Combination with Immunotherapy Feasible?

Pharmaceutics
Background: As a modulator of pre-mRNA splicing, the anti-cancer agent indisulam can induce aberrantly spliced neoantigens, enabling immunologic anti-tumor activity. Consequently, combining indisulam with immunotherapy is expected to be a promising novel
Lisa Arnet, Lisabeth Emilius, Annett Hamann, Maria Carmo-Fonseca, Carola Berking, Jan Dörrie, Niels Schaft   +6 more
doaj   +1 more source

Immunoregulatory factors derived from human tumors. I. Immunologic and biochemical characterization of factors that suppress lymphocyte proliferative and cytotoxic responses in vitro. [PDF]

, 1982
Jack A. Roth, Elizabeth A. Grimm, Rajat Gupta, Robert S. Ames   +3 more
openalex   +1 more source

Integrating electromagnetic cancer stress with immunotherapy: a therapeutic paradigm

Frontiers in Oncology
An array of published cell-based and small animal studies have demonstrated a variety of exposures of cancer cells or experimental carcinomas to electromagnetic (EM) wave platforms that are non-ionizing and non-thermal.
Mark M. Fuster, Mark M. Fuster, Mark M. Fuster, Mark M. Fuster   +3 more
doaj   +1 more source

A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose

npj Vaccines
Filoviruses, including Ebola, Marburg, Sudan, and Taï Forest viruses, are zoonotic pathogens that can cause severe viral hemorrhagic fever and death. Developing vaccines that provide durable, broad immunity against multiple filoviruses is a high global ...
Christina A. Rostad, Inci Yildirim, Carol Kao, Jumi Yi, Satoshi Kamidani, Etza Peters, Kathleen Stephens, Theda Gibson, Hui-Mien Hsiao, Karnail Singh, Paul Spearman, Courtney McCracken, Vivien Agbakoba, Kay M. Tomashek, Johannes B. Goll, Casey E. Gelber, Robert A. Johnson, Sujin Lee, Kristal Maner-Smith, Steven Bosinger, Eric A. Ortlund, Xuemin Chen, Larry J. Anderson, Jens Wrammert, Mehul Suthar, Nadine Rouphael, Evan J. Anderson   +26 more
doaj   +1 more source

Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene [PDF]

, 1998
Sebastian Finke, Beate Trojaneck, Petja Lefterova, Markus Csipai, Ernst Wagner, Ralf Kircheis, Andreas Neubauer, D. Huhn, B. Wittig, IGH Schmidt-Wolf   +9 more
openalex   +1 more source

Gut regulatory T cells mediate immunological tolerance inSalmonella-infected superspreader hosts by suppressing cytotoxic activity of T cells [PDF]

, 2021
LM Massis, Sarah Ruddle, SM Brewer, Ruth Schade, R Narasimhan, JD Honeycutt, Trung H. M. Pham, Joy A. McKenna, SW Brubaker, Phoom Chairatana, Jessica A. Klein, Mar Margalef-Català, MR Amieva, JG Vilches-Moure, DM Monack   +14 more
openalex   +1 more source

Immunological changes in simian immunodeficiency virus (SIVagm)-infected African green monkeys (AGM): expanded cytotoxic T lymphocyte, natural killer and B cell subsets in the natural host of SIVagm

, 2002
Edgar Holznagel, Stephen Norley, Silke Holzammer, Cheick Coulibaly, Reinhard Kurth   +4 more
openalex   +1 more source

Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway1

, 2003
Hisanori Kosuge, Jun‐ichi Suzuki, Ryo Gotoh, Noritaka Koga, Hiroshi Ito, Mitsuaki Isobe, Manabu Inobe, Toshimitsu Uede   +7 more
openalex   +1 more source