Results 11 to 20 of about 878,335 (267)
Journal of Investigative Dermatology, 1988 Human vitiligo is a common depigmenting disorder that is often associated with polyendocrinopathies. The etiology of vitiligo is unknown although there is indirect evidence of a strong association between antimelanocyte antibodies in animal and human ...
David A. Norris +3 more
semanticscholar +1 more source
Search and capture efficiency of dynamic microtubules for centrosome relocation during IS formation [PDF]
Biophysical Journal (2019), 2019 Upon contact with antigen presenting cells (APCs) cytotoxic T lymphocytes (T cells) establish a highly organized contact zone denoted as immunological synapse (IS). The formation of the IS implies relocation of the microtubule organizing center (MTOC) towards the contact zone, which necessitates a proper connection between MTOC and IS via dynamic ...
arxiv +1 more source
Evidence-Based Complementary and Alternative Medicine, 2018 Lycium barbarum polysaccharide (LBP) is the major function component of Lycium barbarum L. and has been previously reported to induce the phenotypic and functional maturation of dendritic cells (DCs) as well as activating T lymphocytes.
W. Wang +8 more
semanticscholar +1 more source
PLoS ONE, 2017 The role of natural killer (NK) cell function in HIV disease especially in the setting of long-term antiretroviral therapy (ART) and viral suppression is not fully understood.
Zhenwu Luo +9 more
semanticscholar +1 more source
Journal of Infectious Diseases, 2017 Increased mortality and morbidity occur among human immunodeficiency virus (HIV)-infected patients in whom CD4+ T-cell counts do not increase despite viral suppression with antiretroviral therapy (ART).
Zhenwu Luo +15 more
semanticscholar +1 more source
CD40L expression permits CD8+ T cells to execute immunologic helper functions.
Blood, 2013 CD8(+) T cells play an essential role in immunity against intracellular pathogens, with cytotoxicity being considered their major effector mechanism. However, we here demonstrate that a major part of central and effector memory CD8(+) T cells expresses ...
M. Frentsch +13 more
semanticscholar +1 more source
Phytochemical study and evaluation of the cytotoxic properties of methanolic extract from Baccharis obtusifolia [PDF]
International Journal of Medicinal Chemistry, 2018, 2019 Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of prostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7).
arxiv +1 more source
Antibody-Dependent Cellular Cytotoxicity Mediated by Cetuximab against Lung Cancer Cell Lines
Clinical Cancer Research, 2007 Purpose: Epidermal growth factor receptor (EGFR) is commonly overexpressed in lung cancer. Cetuximab is a chimeric mouse-human antibody targeted against EGFR. Compared with its inhibitory properties, its immunologic mechanisms have not been well studied.
J. Kurai +12 more
semanticscholar +1 more source
Sensing Danger: Innate Immunology for Intrusion Detection [PDF]
Information Security Technical Report, 12(4), pp 218-227, 2007, 2008 The immune system provides an ideal metaphor for anomaly detection in general and computer security in particular. Based on this idea, artificial immune systems have been used for a number of years for intrusion detection, unfortunately so far with little success. However, these previous systems were largely based on immunological theory from the 1970s
arxiv +1 more source
Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control
Current Opinion in HIV and AIDS, 2011 Purpose of reviewOver the past 2 years, a clearer picture has emerged regarding the properties of HIV-specific CD8+ T cells associated with immunologic control of HIV replication.
Adam R. Hersperger +3 more
semanticscholar +1 more source