Results 21 to 30 of about 936,977 (378)

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

open access: yes, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo   +25 more
core   +1 more source

Assessment of intracanal medications cytotoxicity on L929 fibroblast cells

open access: yesBioscience Journal, 2016
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias   +6 more
doaj   +3 more sources

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

open access: yesBiomaterials Research, 2023
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi   +7 more
doaj   +1 more source

Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]

open access: yes, 2003
Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski   +27 more
core   +2 more sources

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation.

open access: yesBlood, 2001
Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor cooperation with ...
A. Spriel   +6 more
semanticscholar   +1 more source

Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells

open access: yesFrontiers in Immunology, 2013
Natural Killer (NK) cells are able to recognize and kill tumor cells, however whether they contribute to tumor immunosurveillance is still debated. Our previous studies demonstrated the presence of NK cells in human lung tumors.
Mélanie eGillard-Bocquet   +22 more
doaj   +1 more source

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma [PDF]

open access: yes, 2016
Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with limited success. It has been postulated that a low mutation load may lead to a paucity of T cells within the tumor microenvironment (TME).
Alvarez, Hector A.   +13 more
core   +1 more source

Cytotoxic and Immunologic Effects of Methotrexate in Psoriasis

open access: yesJournal of Investigative Dermatology, 1990
Based on recent experience that Cyclosporin A, an immunosuppressive drug, produces marked improvement in psoriasis, possible immunomodulatory activities of methotrexate (MTX) have been reviewed to look for alternate mechanisms of MTX action in psoriasis. It is generally considered that the therapeutic results of MTX in psoriasis are related to a direct
Weinstein, Gerald D.   +2 more
openaire   +2 more sources

Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer-Mediated Cytotoxicity.

open access: yesCancer Research, 2018
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity.
Antoun Al Absi   +14 more
semanticscholar   +1 more source

SDF-1α Reduces Human Natural Killer Cell Cytotoxicity against Chronic Myelogenous Leukemia K562 Cells

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2019
Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness.
Alireza Mardomi   +4 more
doaj   +1 more source

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