Results 31 to 40 of about 55,236 (336)

New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]

, 2015
Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B, Kotova, Svetlana, Wong, Raymond M   +2 more
core   +2 more sources

Cytotoxic Isoantibodies and Immunologic Enhancement in Mice.

Experimental Biology and Medicine, 1966
Summary1. Cytotoxic isoantibodies and hemagglutinins are stimulated in response to H-2 isoantigenic differences between graft and host in mice. 2. This study offers data correlating cytotoxic isoantibody and immunological enhancement. 3. The mechanism of immunological enhancement has been shown to be associated with peripheral as well as central ...
openaire   +2 more sources

In vitro Cytotoxicity in Delayed-Type Hypersensitivity and Immunologic Tolerance.

Experimental Biology and Medicine, 1964
SummaryPicryl chloride was found to exert a lethal effect in vitro on leukocytes, principally lymphocytes, from guinea pigs exhibiting delayed-type skin reactivity to this hapten in the absence of antibody and complement. This reaction was found to be immunologically specific.
D M, LUBAROFF, R E, RITTS
openaire   +2 more sources

NKp46 clusters at the immune synapse and regulates NK cell polarization

Frontiers in Immunology, 2015
Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. The activity of NK cells is tightly regulated by a repertoire of cell-surface expressed inhibitory and activating receptors.
Uzi eHadad, Uzi eHadad, Timothy J Thauland, Olivia M Martinez, Manish J Butte, Angel ePorgador, Sheri M Krams   +6 more
doaj   +1 more source

The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands

Frontiers in Immunology, 2018
NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins.
Jianmin Zuo, Fiyaz Mohammed, Paul Moss
doaj   +1 more source

Negative Regulation and Protective Function of Natural Killer Cells in HIV Infection: Two Sides of a Coin

Frontiers in Immunology, 2022
Natural killer (NK) cells play an important immunologic role, targeting tumors and virus-infected cells; however, NK cells do not impede the progression of human immunodeficiency virus (HIV) infection.
Yu Sun, Jie Zhou, Yongjun Jiang
doaj   +1 more source

Analogue peptides for the immunotherapy of human acute myeloid leukemia [PDF]

, 2015
Accepted manuscript. The final publication is available at: http://link.springer.com/article/10.1007%2Fs00262-015-1762-9The use of peptide vaccines, enhanced by adjuvants, has shown some efficacy in clinical trials.
A Driessche Van, A Gros, A Scardino, A Serrano, A Sevko, A Snyder, A Tsuboi, AB Bakker, Aleksandrs Malinovskis, Andrew Mead, AT Cheuk, AW Purcell, B Engels, B Falini, B Maecker, B Maecker, B Uttenthal, BA Guinn, BA Guinn, Barbara-ann Guinn, C Chaise, C Maccalli, CL Slingluff Jr, D Cilloni, D Mason, DA Gross, DE Speiser, DH Chang, DJ Schwartzentruber, E Estey, E Romano, F Ghiringhelli, FS Hodi, G Khan, H Kobayashi, H Ohminami, HJ Kolb, HJ Stauss, I Bellantuono, J Bae, J Bae, J Fourcade, J Greiner, J Greiner, J Kronke, J Pinilla-Ibarz, J Pinilla-Ibarz, JH Sampson, JJ Molldrem, JL Chen, JL Chen, JN Kochenderfer, JS Ko, JW Wells, K Inoue, K Inoue, K Rezvani, K Rezvani, KM Zirlik, L Chan, L Fong, L Gao, LV Ly, M Harndahl, M Kapp, M Subklewe, MA Cheever, MG Warnock, MM Gubin, MR Parkhurst, MS Bijker, N Hardwick, Nicola R. Hardwick, O Christensen, O Hamid, P Brossart, P Bruggen van der, P Keskinen, PG Maslak, PG Maslak, R Cibotti, RA Padua, RF Schlenk, RJ May, S Frankild, S Hofmann, S Narayan, S Ochsenreither, S Pascolo, S Suekane, S Walter, SH Burg van der, SK Singh, SL Topalian, SP Adams, Susanne Hofmann, T Lovgren, U Keilholz, U Sahin, V Bhardwaj, WS Meng, Y Oka, Z Trajanoski   +102 more
core   +2 more sources

Immune modulation of i.v. immunoglobulin in women with reproductive failure

Reproductive Medicine and Biology, 2018
Background The mechanism of maternal immune tolerance of the semi‐allogenic fetus has been explored extensively. The immune reaction to defend from invasion by pathogenic microorganisms should be maintained during pregnancy.
Ae R. Han, Sung K. Lee
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

CVD-grown monolayer MoS2 in bioabsorbable electronics and biosensors [PDF]

, 2018
Transient electronics entails the capability of electronic components to dissolve or reabsorb in a controlled manner when used in biomedical implants.
Ahn, Jong-Hyun, Chen, Xiang, Jeon, Seunghyun, Kang, Minpyo, Kang, Seung-Kyun, Koo, Jahyun, Lee, Kyung-Mi, MacEwan, Matthew R., Park, Gayoung, Park, Yong Ju, Ray, Wilson Z., Rogers, John A., Shin, Jiho, Shinde, Sachin M., Yan, Ying   +14 more
core   +3 more sources