Results 1 to 10 of about 122,785 (104)

Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management

Frontiers in Immunology, 2021
Primary immune regulatory disorders (PIRD) are associated with autoimmunity, autoinflammation and/or dysregulation of lymphocyte homeostasis. Autoimmune lymphoproliferative syndrome (ALPS) is a PIRD due to an apoptotic defect in Fas-FasL pathway and ...
Marta López-Nevado, L. González-Granado, R. Ruiz-García, D. Pleguezuelo, O. Cabrera-Marante, N. Salmón, P. Blanco-Lobo, N. Domínguez-Pinilla, R. Rodríguez‐Pena, E. Sebastián, J. Cruz-Rojo, P. Olbrich, J. Ruiz-Contreras, E. Paz-Artal, O. Neth, L. Allende   +15 more
semanticscholar   +1 more source

Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.

Blood, 2008
TNFRSF13B encodes transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), a B cell- specific tumor necrosis factor (TNF) receptor superfamily member.
U. Salzer, C. Bacchelli, S. Buckridge, Q. Pan-Hammarström, Stephanie Jennings, V. Lougaris, A. Bergbreiter, T. Hagena, Jennifer Birmelin, A. Plebani, A. Webster, H. Peter, D. Suez, H. Chapel, A. Mclean-Tooke, G. Spickett, Stephanie Anover-Sombke, H. Ochs, S. Urschel, B. Belohradsky, S. Ugrinovic, D. Kumararatne, T. C. Lawrence, A. Holm, J. Franco, I. Schulze, P. Schneider, E. Gertz, A. Schäffer, L. Hammarström, A. Thrasher, H. Gaspar, B. Grimbacher   +32 more
semanticscholar   +1 more source

HIV Controllers With Different Viral Load Cutoff Levels Have Distinct Virologic and Immunologic Profiles

Journal of Acquired Immune Deficiency Syndromes, 2015
Background:The mechanisms behind natural control of HIV replication are still unclear, and several studies pointed that elite controllers (ECs) are a heterogeneous group.
F. H. Côrtes, C. P. Passaes, G. Bello, S. L. Teixeira, C. Vorsatz, Dunja Z. Babič, M. Sharkey, B. Grinsztejn, V. Veloso, M. Stevenson, M. Morgado   +10 more
semanticscholar   +1 more source

Correlation between Traditional Chinese Medicine Symptom Patterns and the Renal Function, Immunologic Function Index, and Blood Coagulation Index in Patients with Henoch-Schönlein Purpura Nephritis

Evidence-Based Complementary and Alternative Medicine, 2018
Objective We investigate the correlation between the patterns of traditional Chinese medicine (TCM) syndromes and the damage of renal function, immunologic function index, and blood coagulation index in patients with Henoch-Schönlein purpura nephritis ...
Wanyu Dang, Huimin Yan, Xiaoming Wu, Xiaofang Zhen, Linyi Hou   +4 more
semanticscholar   +1 more source

Antiretroviral Therapy Adherence, Virologic and Immunologic Outcomes in Adolescents Compared With Adults in Southern Africa

Journal of Acquired Immune Deficiency Syndromes, 2009
Objective:To determine adherence to and effectiveness of antiretroviral therapy (ART) in adolescents vs. adults in southern Africa. Design:Observational cohort study.
J. Nachega, M. Hislop, Hoang Nguyen, D. Dowdy, R. Chaisson, L. Regensberg, M. Cotton, G. Maartens   +7 more
semanticscholar   +1 more source

Pathogenic mechanisms and clinical implications of congenital neutropenia syndromes

Current Opinion in Allergy and Clinical Immunology, 2013
Purpose of reviewThe purpose of this review is to summarize pathogenic mechanisms and clinical implications of the most illustrative genetic entities of congenital neutropenia syndromes. Recent findingsCongenital neutropenia comprise monogenetic entities
F. Hauck, C. Klein
semanticscholar   +1 more source

Effect of Directly Observed Therapy for Highly Active Antiretroviral Therapy on Virologic, Immunologic, and Adherence Outcomes: A Meta-Analysis and Systematic Review

Journal of Acquired Immune Deficiency Syndromes, 2010
Introduction:Directly observed therapy of highly active antiretroviral therapy (DOT-HAART) is a feasible adherence intervention. Prospective DOT-HAART studies have shown mixed results, and optimal target groups have yet to be defined. We performed a meta-
J. E. Hart, C. Jeon, L. Ivers, H. Behforouz, A. Caldas, P. Drobac, Sonya S. Shin   +6 more
semanticscholar   +1 more source

Immunological Deficiency Syndromes [Abridged] [PDF]

, 1968
J R Hobbs
  +8 more sources

Association of Immunologic and Virologic Factors With Myocardial Infarction Rates in a US Healthcare System

Journal of Acquired Immune Deficiency Syndromes, 2010
Background:The effects of immunologic and virologic factors on acute myocardial infarction (AMI) rates in patients with HIV are unclear. Methods:HIV-infected patients in a US healthcare system were assessed for AMI. Results:Of 6517 patients with HIV, 273
V. Triant, S. Regan, Hang Lee, P. Sax, J. Meigs, S. Grinspoon   +5 more
semanticscholar   +1 more source

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]

Science Translational Medicine, American Association for the Advancement of Science, 2017, 9 (405), pp.eaal5088, 2017
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv   +1 more source