Results 131 to 140 of about 138,687 (371)

Parasitic lung diseases (Editorial) [PDF]

open access: yes, 1997
Lung diseases that result from infestations with Pleuropulmonary amoebiasis: protozoal and helminthic parasites are important public health problems worldwide.
Vijayan, V K
core  

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

open access: yesAdvanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng   +4 more
wiley   +1 more source

Pathogenic mechanisms and clinical implications of congenital neutropenia syndromes

open access: yesCurrent Opinion in Allergy and Clinical Immunology, 2013
F. Hauck, C. Klein
semanticscholar   +1 more source

Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

open access: yesAdvanced Science, EarlyView.
This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin   +10 more
wiley   +1 more source

Effect of Directly Observed Therapy for Highly Active Antiretroviral Therapy on Virologic, Immunologic, and Adherence Outcomes: A Meta-Analysis and Systematic Review

open access: yesJournal of Acquired Immune Deficiency Syndromes, 2010
J. E. Hart   +6 more
semanticscholar   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou   +13 more
wiley   +1 more source

Association of Immunologic and Virologic Factors With Myocardial Infarction Rates in a US Healthcare System

open access: yesJournal of Acquired Immune Deficiency Syndromes, 2010
V. Triant   +5 more
semanticscholar   +1 more source

Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan   +7 more
wiley   +1 more source

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