Results 1 to 10 of about 412,483 (262)
Desensitization: Overcoming the Immunologic Barriers to Transplantation [PDF]
Journal of Immunology Research, 2017 HLA (Human Leucocyte Antigen) sensitization is a significant barrier to successful kidney transplantation. It often translates into difficult crossmatch before transplant and increased risk of acute and chronic antibody mediated rejection after ...
Supreet Sethi +5 more
doaj +6 more sources
Excellent outcome after desensitization in high immunologic risk kidney transplantation.
PLoS ONE, 2019 INTRODUCTION:HLA-incompatible (HLAi) and ABO-incompatible (ABOi) kidney transplantation (KT) has been on the increase over the last decade. However, there are wide variations in outcomes from these procedures.
Jeong-Hoon Lim +10 more
doaj +6 more sources
Immunologic Desensitization [PDF]
Duodecim lääketieteellinen aikakauskirja, 2020 E Valovirta
semanticscholar +3 more sources
Immunological mechanisms for desensitization and tolerance in food allergy [PDF]
Seminars in Immunopathology, 2012 Food allergy is a major public health concern in westernized countries, estimated to affect 5 % of children and 3-4 % of adults. Allergen-specific immunotherapy for food allergy is currently being actively evaluated, but is still experimental. The optimal protocol, in terms of the route of administration of the food, target maintenance dose, and ...
Rima, Rachid, Dale T, Umetsu
openaire +4 more sources
HLA Desensitization in Solid Organ Transplantation: Anti-CD38 to Across the Immunological Barriers [PDF]
Frontiers in Immunology, 2021 The presence of anti-human leucocyte antigen (HLA) antibodies in the potential solid organ transplant recipient’s blood is one of the main barriers to access to a transplantation. The HLA sensitization is associated with longer waitlist time, antibody mediated rejection and transplant lost leading to increased recipient’s morbidity and mortality ...
Nizar Joher +5 more
openaire +5 more sources
Oral desensitizing treatment in food allergy: clinical and immunological results [PDF]
Alimentary Pharmacology & Therapeutics, 2003 SummaryBackground : The possibility of inducing oral desensitization in patients with food allergy is still controversial and no standardized programmes are yet available.Aim : To evaluate the safety and efficacy of oral desensitization in patients with allergy induced by the most common food allergens.Methods : Fifty‐nine patients with food allergy ...
Patriarca, Giampiero +9 more
+6 more sources
Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization [PDF]
Allergy, Asthma & Immunology Research, 2017 This study aimed to evaluate the safety and efficacy to induce clinical desensitization to cow's milk (CM) of an oral immunotherapy (OIT) protocol in a pediatric population with cow's milk allergy (CMA). In addition, the immune responses against β-casein, of peripheral blood mononuclear cells (PBMCs) from CMA patients, before and after the protocol ...
Perezábad, Laura +5 more
openaire +6 more sources
Novel pretransplant desensitization strategies in heart transplantation [PDF]
JHLT OpenAllosensitization remains a major barrier in thoracic organ transplantation, limiting access to transplantation and increasing waitlist mortality and post-transplant morbidity.
Guillaume Coutance, MD, PhD +2 more
doaj +2 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2022 Aspirin-exacerbated respiratory disease (AERD) is a chronic inflammatory disease. It is defined by asthma, chronic rhinosinusitis with nasal polyposis, and a hypersensitivity reaction to aspirin or nonsteroidal anti-inflammatory drugs. Aspirin desensitization (AD) has been confirmed as an effective treatment to control AERD inflammation through the ...
Hossein Esmaeilzadeh +5 more
openaire +4 more sources
Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons [PDF]
Frontiers in ImmunologyWith the recent FDA approval of the anti-IgE biologic, omalizumab, in 2024 for the treatment of food allergy, it is critical to consider the advantages and disadvantages of anti-IgE and allergen-specific immunotherapies (AITs) to help determine optimal ...
Michael D. Kulis +5 more
doaj +2 more sources