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Allergic and immunologic evaluation of children with celiac disease [PDF]

open access: yesFrontiers in Pediatrics
IntroductionCeliac disease (CD) and allergic diseases are immune-mediated disorders with overlapping clinical and immunologic features. The association between CD and selective immunoglobulin (Ig) A deficiency (sIgAD) is well-established, but limited ...
Duygu Demirtaş Güner, Kübra Baskın
doaj   +2 more sources

Considerations for biologics as front-line treatment in allergic diseases [PDF]

open access: yesFrontiers in Immunology
The therapeutic landscape of allergic diseases has been transformed by the advent of biologics targeting key immunologic pathways. These therapies offer disease-modifying potential across a spectrum of conditions including asthma, atopic dermatitis ...
Akash Kothari   +3 more
doaj   +2 more sources

Mutation update of SERPING1 related to hereditary angioedema in the Chinese population

open access: yesHereditas, 2022
Background Hereditary angioedema (HAE) is a rare disease characterized by recurrent attacks of severe swellings of the skin and submucosa. More than 900 variants of the SERPING1 gene associated with HAE have been identified.
Xue Wang   +4 more
doaj   +1 more source

Serum IgE profiles in Chinese pollinosis patients with grass pollen sensitisation

open access: yesWorld Allergy Organization Journal, 2022
Purpose: Pollen from trees, grasses, and weeds is a common allergen source. The characteristics of pollen allergy in China are obviously different from Europe.
Jun-Da Li   +7 more
doaj   +1 more source

Altered Urinary Metabolomics in Hereditary Angioedema

open access: yesMetabolites, 2022
Hereditary angioedema (HAE) is a rare and potentially life-threatening disease with heterogeneous clinical symptoms. The metabolomic profile of HAE remains unknown.
Xue Wang, Yuxiang Zhi
doaj   +1 more source

The natural course of hereditary angioedema in a Chinese cohort

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Hereditary angioedema (HAE) is a rare disease with potential life-threatening risks. To study the natural course of HAE under therapy-free conditions throughout patient life is essential for practitioners and patients to avoid possible risk ...
Yang Cao, Shuang Liu, Yuxiang Zhi
doaj   +1 more source

Clinical Phenotypes of Sepsis in a Cohort of Hospitalized Patients According to Infection Site

open access: yesCritical Care Explorations, 2023
OBJECTIVES:. Clinical sepsis phenotypes may be defined by a wide range of characteristics such as site of infection, organ dysfunction patterns, laboratory values, and demographics.
Adam R. Schertz, MD, MS   +4 more
doaj   +1 more source

The efficacy of a novel smart watch on medicine adherence and symptom control of allergic rhinitis patients: Pilot study

open access: yesWorld Allergy Organization Journal, 2023
Background: Allergic rhinitis (AR) is a common allergic airway disorder that is often poorly managed. There is an urgent need to enhance medication adherence in order to improve treatment outcomes in patients with AR.
Lisha Li, MD   +5 more
doaj   +1 more source

Throat microbiota alterations in patients with hereditary angioedema

open access: yesWorld Allergy Organization Journal, 2022
Background: Hereditary angioedema (HAE) is a rare disease characterized by recurrent episodes of cutaneous and submucosal edema. The clinical course of HAE is heterogeneous and unpredictable.
Xue Wang, MD   +2 more
doaj   +1 more source

Validation of diagnostic and predictive biomarkers for hereditary angioedema via plasma N‐glycomics

open access: yesClinical and Translational Allergy, 2021
Background Hereditary angioedema (HAE) is a rare disease with heterogeneous clinical symptoms. It is vitally important to predict whether an HAE patient will develop severe symptoms in clinical practice, but there are currently no predictive biomarkers ...
Zejian Zhang   +11 more
doaj   +1 more source

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