Results 191 to 200 of about 161,133 (312)

Autosomal-dominant hyper-IgE syndrome is associated with appearance of infections early in life and/or neonatal rash: Evidence from the Italian cohort of 61 patients with elevated IgE [PDF]

, 2019
Badolato R, Cancrini C, Carrabba M, Cortesi M, Cossu F, Dellepiane RM, Dotta L, Giacomelli M, Giardino G, IPINET (Italian Network for Primary Immunodeficiencies), Lorenzini T, Pietrogrande MC, Pignata C, Plebani A, Rivellini V, Scomodon O, Soresina A, Specchia F   +17 more
core   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Normal Immune Function in a Newborn With Early Identification of a <i>SAMD9</i> Mutation Presenting With Growth Restriction, Thrombocytopenia, and Primary Adrenal Insufficiency. [PDF]

Clin Case Rep
Gao KM, Huang QYJ, Huang P, Muzaffar A, Beheshti R, Wood R, Dantzer J, Gutierrez MJ.   +7 more
europepmc   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Immunodeficiency in Children With Invasive Pneumococcal Disease. [PDF]

Cureus
Almesfer AM, AlSaiary MM, Alharbi FM, Alradhi SI.   +3 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Disseminated Histoplasmosis in Very Early Diagnosed De Novo STAT3-HIES. [PDF]

J Clin Immunol
Sanosyan A, Hazan R, Freeman AF, Schmitt EG, Horner CC.   +4 more
europepmc   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Activated PI3Kδ syndrome in inborn errors of immunity: diagnostic strategies and clinical challenges. [PDF]

Front Immunol
Bozkurt S, Ozturk N, Altunbas MY, Can S, Amirov R, Mahmudov R, Colak BC, Karabiber E, Baronio M, Lougaris V, Tessarin G, Bilgic-Eltan S, Ozen A, Baris S, Karakoc-Aydiner E.   +14 more
europepmc   +1 more source