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Multiple Levels of Immunological Memory and Their Association with Vaccination [PDF]
Vaccines, 2021 Immunological memory is divided into many levels to counteract the provocations of diverse and ever-changing infections. Fast functions of effector memory and the superposition of both quantitatively and qualitatively plastic anticipatory memory ...
Zsófia Bugya +5 more
doaj +3 more sources
Heterogeneous magnitude of immunological memory to SARS‐CoV‐2 in recovered individuals [PDF]
Clinical & Translational Immunology, 2021 Objective Although the adaptive immune response to SARS‐CoV‐2 has been characterised in the acute and early convalescent phase of the disease, few studies explore whether natural infection elicits long‐lasting immunological memory in recovered ...
Alessio Mazzoni +15 more
doaj +3 more sources
T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance. [PDF]
Elife, 2023 A defining feature of successful vaccination is the ability to induce long-lived antigen-specific memory cells. T follicular helper (Tfh) cells specialize in providing help to B cells in mounting protective humoral immunity in infection and after ...
Gao X +27 more
europepmc +2 more sources
Immunological memory to SARS-CoV-2 infection and COVID-19 vaccines. [PDF]
Immunol Rev, 2022 Immunological memory is the basis of protective immunity provided by vaccines and previous infections. Immunological memory can develop from multiple branches of the adaptive immune system, including CD4 T cells, CD8 T cells, B cells, and long‐lasting ...
Sette A, Crotty S.
europepmc +2 more sources
An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory. [PDF]
Nat Cell Biol, 2022 The common view is that T lymphocytes activate telomerase to delay senescence. Here we show that some T cells (primarily naïve and central memory cells) elongated telomeres by acquiring telomere vesicles from antigen-presenting cells (APCs) independently
Lanna A +14 more
europepmc +2 more sources
Immunology & Cell Biology, 2019 Immunological memory is a critical evolutionary adaptation of the immune system that mediates more rapid and effective responses to previously encountered antigens. Immunological memory is often thought of as being mediated by conventional adaptive cells:
Joanna R, Kirman +2 more
openaire +3 more sources
SARS-CoV-2 infection generates tissue-localized immunological memory in humans. [PDF]
Sci Immunol, 2021 Description SARS-CoV-2–specific memory cells persist in multiple sites months after infection, particularly in lungs and associated lymph nodes. Adaptive immune responses to SARS-CoV-2 infection have been extensively characterized in blood; however, most
Poon MML +24 more
europepmc +2 more sources
International Journal of Infectious Diseases, 2021 Background: The efficacy of COVID-19 vaccines to generate immunological memory post-vaccination has not previously been studied. Objective: To assess immunological memory in previously SARS-CoV-2 infected individuals after a single dose of mRNA vaccine ...
Mitnala Sasikala +7 more
doaj +2 more sources
Central European Journal of Immunology, 2018 This article reviews immunological memory cells, currently represented by T and B lymphocytes and natural killer (NK) cells, which determine a rapid and effective response against a second encounter with the same antigen. Among T lymphocytes, functions of memory cells are provided by their subsets: central memory, effector memory, tissue-resident ...
Ratajczak, Weronika +3 more
openaire +3 more sources
Immunological memory≠protective immunity [PDF]
Cellular and Molecular Life Sciences, 2018 So-called ‘immunological memory' is, in my view, a typical example where a field of enquiry, i.e. to understand long-term protection to survive reexposure to infection, has been overtaken by ‘l'art pour l'art' of ‘basic immunology'.
Zinkernagel, Rolf
core +5 more sources