Results 211 to 220 of about 2,376,976 (334)

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

CRISPR Immunological Memory Requires a Host Factor for Specificity.

Molecules and Cells, 2016
James K. Nuñez, L. Bai, Lucas B. Harrington, Tracey L. Hinder, J. Doudna   +4 more
semanticscholar   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Immunological memory in a teleost fish: common carp IgM⁺ B cells differentiate into memory and plasma cells. [PDF]

Front Immunol
Chan JTH, Picard-Sánchez A, Dedić N, Majstorović J, Rebl A, Holzer AS, Korytář T.   +6 more
europepmc   +1 more source

Vinorelbine and Intermittent Cyclophosphamide Sensitize an Aggressive Myc-Driven B-Cell Lymphoma to Anti-PD-1 by an Immunological Memory Effective against Tumor Re-Challenge. [PDF]

J Clin Med, 2023
Orecchioni S, Falvo P, Talarico G, Mitola G, Bravetti G, Mancuso P, Nicoli P, Bertolini F.   +7 more
europepmc   +1 more source

Patterns of cytokine gene expression of naïve and memory T lymphocytes in vivo. [PDF]

, 2002
Bailey, S., Gossner, Anton, Hopkins, John, Hunter, Nora   +3 more
core  

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Infection-induced trained immunity: a twist in paradigm of innate host defense and generation of immunological memory. [PDF]

Infect Immun
Bahl A, Pandey S, Rakshit R, Kant S, Tripathi D.   +4 more
europepmc   +1 more source

Evasion of Immunological Memory by S. aureus Infection: Implications for Vaccine Design. [PDF]

Front Immunol, 2021
Teymournejad O, Montgomery CP.
europepmc   +1 more source