Results 21 to 30 of about 2,376,976 (334)
We address whether T cell responses induced by different vaccine platforms (mRNA-1273, BNT162b2, Ad26.COV2.S, and NVX-CoV2373) cross-recognize early SARS-CoV-2 variants. T cell responses to early variants were preserved across vaccine platforms.
A. Tarke +16 more
semanticscholar +1 more source
Immune Imprinting and Implications for COVID-19
Immunological memory is the key source of protective immunity against pathogens. At the current stage of the COVID-19 pandemic, heterologous combinations of exposure to viral antigens during infection and/or vaccination shape a distinctive immunological ...
Zhiqian Zhou, Julia Barrett, Xuan He
doaj +1 more source
During pregnancy, the maternal immune system undergoes major adaptive modifications that are necessary for the acceptance and protection of the fetus.
Xiaobo Huang +12 more
semanticscholar +1 more source
Development and function of protective and pathologic memory CD4 T cells [PDF]
Immunological memory is one of the defining features of the adaptive immune system. As key orchestrators and mediators of immunity, CD4 T cells are central to the vast majority of adaptive immune responses.
Jaigirdar, Shafqat Ahrar +1 more
core +6 more sources
Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. [PDF]
While immunological memory has long been considered the province of T- and B-lymphocytes, it has recently been reported that innate cell populations are capable of mediating memory responses. We now show that an innate memory immune response is generated
Geoffrey O Gillard +7 more
doaj +1 more source
Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi +51 more
core +11 more sources
How does cross-reactive stimulation affect the longevity of CD8+ T cell memory? [PDF]
Immunological memory--the ability to "remember" previously encountered pathogens and respond faster upon re-exposure is a central feature of the immune response in vertebrates.
Vitaly V Ganusov +3 more
doaj +1 more source
Immunological memory can be defined as the ability to mount a response of greater magnitude and with faster kinetics upon re-encounter of the same antigen. We have previously reported that a booster dose of a protein antigen given 15 days after the first
Francesca Mantile +3 more
doaj +1 more source
NFκB signaling in T cell memory
Memory T cells play an essential role in protecting against infectious diseases and cancer and contribute to autoimmunity and transplant rejection. Understanding how they are generated and maintained in the context of infection or vaccination holds ...
Mark A. Daniels +7 more
doaj +1 more source
Childhood vaccination plays critical role in protecting infants from several dreaded diseases. Of the global 15 million preterm (PT) infants with compromised immune system born annually, India contributes to >3.5 million.
Archana Kulkarni-Munje +6 more
doaj +1 more source

