Results 221 to 230 of about 31,523 (247)
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Blood, 2009
Abstract Abstract SCI-47 Transfusion medicine has long recognized that there is significant variation in the human immune response to red blood cell (RBC) transfusions.1 All allogeneic RBC transfusions expose the recipient to multiple foreign antigens, but very few RBC transfusions induce a detectable humoral immune ...
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Abstract Abstract SCI-47 Transfusion medicine has long recognized that there is significant variation in the human immune response to red blood cell (RBC) transfusions.1 All allogeneic RBC transfusions expose the recipient to multiple foreign antigens, but very few RBC transfusions induce a detectable humoral immune ...
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Frontiers in ImmunologyIntroductionImmunological non-responders (INR) are people living with HIV (PLHIV) who fail to fully restore CD4+ T-cell counts despite complete viral suppression with antiretroviral therapy (ART). INR are at higher risk for non-HIV related morbidity and mortality.
Adriana Navas +2 more
exaly +6 more sources
Nature, 1983
Cromoglycate, which inhibits IgE-mediated degranulation of mast cells and a basophilic rat tumour cell line (RBL-2H3) (ref.3), is a drug widely used in the treatment of allergic asthma. We have demonstrated the presence of specific binding sites for that drug on the membranes of basophils and mast cells and more recently, we have succeeded in isolating
N, Mazurek +3 more
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Cromoglycate, which inhibits IgE-mediated degranulation of mast cells and a basophilic rat tumour cell line (RBL-2H3) (ref.3), is a drug widely used in the treatment of allergic asthma. We have demonstrated the presence of specific binding sites for that drug on the membranes of basophils and mast cells and more recently, we have succeeded in isolating
N, Mazurek +3 more
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Blood, 2008
AbstractRed blood cell (RBC) transfusion is unique as a common large-scale intravenous introduction of foreign tissue and provides a valuable opportunity to study human immunologic response to intravenous foreign antigen. Patients receiving RBC transfusions are at risk of forming alloantibodies against donor RBC antigens, and valid estimates of ...
John M, Higgins, Steven R, Sloan
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AbstractRed blood cell (RBC) transfusion is unique as a common large-scale intravenous introduction of foreign tissue and provides a valuable opportunity to study human immunologic response to intravenous foreign antigen. Patients receiving RBC transfusions are at risk of forming alloantibodies against donor RBC antigens, and valid estimates of ...
John M, Higgins, Steven R, Sloan
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Acta medica portuguesa, 2001
An important reduction in morbidity and mortality due to hepatitis B was achieved with the discovery of an effective vaccine. However, 2 to 10% of healthy adults do not respond to vaccination with the production of protective levels of antibody anti-HBs (assumed as protective, concentrations of ab. anti-HBs > 10 UI/L). Therefore, the aim of the present
I, Ramos +5 more
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An important reduction in morbidity and mortality due to hepatitis B was achieved with the discovery of an effective vaccine. However, 2 to 10% of healthy adults do not respond to vaccination with the production of protective levels of antibody anti-HBs (assumed as protective, concentrations of ab. anti-HBs > 10 UI/L). Therefore, the aim of the present
I, Ramos +5 more
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P388 Immunological changes in IBD patients responding to low-dose naltrexone treatment
Journal of Crohn's and Colitis, 2012P387 Factors associated with successful rescue therapy with infliximab for acute severe ulcerative colitis Z. Heetun1, K. Nanda1, D. Keegan2, K. Byrne3, G. Cullen1, D. O’Donoghue4, H. Mulcahy5, G. Doherty2 *. 1St Vincent’s University Hospital, Dept of Gastroenterology, Dublin, Ireland, 2St Vincent’s University Hospital, Department of Gastroenterology ...
C. de Haar +3 more
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Modulation of TIM-3 expression on NK and T cell subsets in HIV immunological non-responders
Clinical Immunology, 2015Highly active antiretroviral therapy (HAART) for the treatment of HIV infection sustains viral suppression and increases CD4(+) T cells in HIV patients. However, in 10-25% of subjects, known as immunological non-responders (INRs), HAART does not increase CD4 count.
Alan Landay +2 more
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Frontiers in BioscienceBackground: Regulatory T-cells (Tregs) play a crucial role in maintaining immune homeostasis, but their dynamics are altered in a subset of people living with Human Immunodeficiency Virus (HIV) known as immunological non-responders (INRs). INRs fail to reconstitute CD4+ T-cell counts despite viral suppression.
Souheil-Antoine Younes +4 more
exaly +4 more sources
HIV-infected immunologic non-responders: can we provide a helping hand?
Enfermedades Infecciosas y Microbiología Clínica, 2008baseline viral load, history of opportunistic infection, co-morbidities, and age. Potential mechanisms underlying the low-level regeneration of CD4 cells in immune non-responders include deficiencies in the regeneration of central memory CD4 cells and excessive apoptosis8.
Caryn G. Morse, Joseph A. Kovacs
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Veterinary Immunology and Immunopathology, 2010
Rhodococcus equi is a facultative intracellular bacterial pathogen of horses; infected foals develop pyogranulomatous pneumonia, however adult horses are largely unaffected. R. equi infects and proliferates within host macrophages and dendritic cells (DCs).
M C, Heller, K A, Jackson, J L, Watson
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Rhodococcus equi is a facultative intracellular bacterial pathogen of horses; infected foals develop pyogranulomatous pneumonia, however adult horses are largely unaffected. R. equi infects and proliferates within host macrophages and dendritic cells (DCs).
M C, Heller, K A, Jackson, J L, Watson
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