Results 61 to 70 of about 47,462 (201)

Steroid Sparing Effect of 300IR House Dust Mite Sublingual Immunotherapy Tablet in Mite Allergic Rhinitis

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Background In a large randomized controlled trial (NCT02443805) in moderate‐to‐severe house dust mite (HDM) allergic rhinitis (AR) patients with/without controlled asthma, the 300IR HDM sublingual immunotherapy (SLIT) tablet confirmed its efficacy in reducing symptoms and rescue medication (RM) use.
Oliver Pfaar, Pascal Demoly, Philippe Gevaert, Ludger Klimek, Carmen Vidal, Margitta Worm, Randolf Brehler, Thomas B. Casale, Giorgio Walter Canonica   +8 more
wiley   +1 more source

Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification

mBio, 2014
Measurements of the presence of prions in biological tissues or fluids rely more and more on cell-free assays. Although protein misfolding cyclic amplification (PMCA) has emerged as a valuable, sensitive tool, it is currently hampered by its lack of ...
Mohammed Moudjou, Pierre Sibille, Guillaume Fichet, Fabienne Reine, Jérôme Chapuis, Laetitia Herzog, Emilie Jaumain, Florent Laferrière, Charles-Adrien Richard, Hubert Laude, Olivier Andréoletti, Human Rezaei, Vincent Béringue   +12 more
doaj   +1 more source

The impact of whole lung irradiation in lung metastatic rhabdomyosarcoma: A pooled analysis of two European trials and one European registry

Cancer, Volume 132, Issue 15, 1 August 2026.
ABSTRACT Background Lung metastases in patients with metastatic rhabdomyosarcoma (RMS) have not been treated uniformly across Europe. This provides comparison of the impact of whole lung irradiation (WLI). Methods Lung‐metastatic patients included in the Cooperative Weichteilsarkom Studiengruppe‐IV 2002, European Pediatric Soft Tissue Sarcoma Study ...
Amadeus T. Heinz, Philip Heesen, Johannes H. M. Merks, Véronique Minard‐Colin, Martin Ebinger, Alison L. Cameron, Semi Harrabi, Henry Mandeville, Reineke A. Schoot, Jörg Fuchs, Gabriela Guillen, Ewa Koscielniak, Julia C. Chisholm, Monika Sparber‐Sauer, Gianni Bisogno   +14 more
wiley   +1 more source

Checkliste Immunologie

244249Die hier vorgestellte Checkliste hilft dem Labor bei der Erfüllung der Forderungen der Norm DIN/EN/ISO 15189-2014 in allen Bereichen der immunologischen Diagnostik im medizinischen Labor ...
Frey, Oliver, Sack, Ulrich, Skriner, Karl, Penz, Monika-Gabriele, Gruber, Rudolf, Tárnok, Attila, Steinmann, Jörg, Dorn-Beineke, Alexandra, Schmidt, Enno, Kirschfink, Michael   +9 more
core   +1 more source

Characterization and effective expansion of CD4−CD8− TCRαβ+ T cells from individuals living with type 1 diabetes

Molecular Therapy: Methods & Clinical Development
CD4−CD8− TCRαβ+ (double-negative [DN]) T cells represent a rare T cell population that promotes immunological tolerance through various cytotoxic mechanisms.
J. Ernesto Fajardo-Despaigne, Félix Lombard-Vadnais, Adam-Nicolas Pelletier, Aïnhoa Olazabal, Lucie Boutin, Sarah Pasquin, Valérie Janelle, Laurent Legault, Jean-Sébastien Delisle, Erin E. Hillhouse, Lise Coderre, Sylvie Lesage   +11 more
doaj   +1 more source

Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase

Clinical and Developmental Immunology, 2012
Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with fibrosis and a prominent inflammatory infiltrate in the desmoplastic stroma. Moreover, in PDAC, an epithelial-to-mesenchymal transition (EMT) is observed.
Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida   +6 more
doaj   +1 more source

Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]

, 1975
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
Koszinowski, Ulrich H., Bandlow, G.
core   +1 more source

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

Frontiers in Immunology, 2017
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin, Elina Aleksejeva, Armel Houel, Valérie Briolat, Valérie Briolat, Corinne Torhy, Aurélie Lunazzi, Jean-Pierre Levraud, Jean-Pierre Levraud, Pierre Boudinot   +9 more
doaj   +1 more source

The Role of Formylpeptide Receptors, C5a Receptors, and Cytosolic-Free Calcium in Neutrophil Priming

, 1990
Polymorphonuclear leukocytes (PMNL) exposed to chemoattractants or cytokines change their functional capacity. The effect of endotoxin-activated serum as a priming agent on human PMNL was tested.
Reber, Anne-Marie, Dahinden, Clemens A., Zimmerli, Werner   +2 more
core   +1 more source

The carRS-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems

Scientific Reports
Antimicrobial peptides are small cationic molecules produced by eukaryotic cells to combat infection, as well as by bacteria for niche competition. Polymyxin B (PmB), a cyclic antimicrobial peptide, is used prophylactically in livestock and as a last ...
Annabelle Mathieu-Denoncourt, Gregory B Whitfield, Antony T Vincent, Cécile Berne, Julien Pauzé-Foixet, Feriel C Mahieddine, Yves V Brun, Marylise Duperthuy   +7 more
doaj   +1 more source