Results 61 to 70 of about 4,425 (147)

Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification

mBio, 2014
Measurements of the presence of prions in biological tissues or fluids rely more and more on cell-free assays. Although protein misfolding cyclic amplification (PMCA) has emerged as a valuable, sensitive tool, it is currently hampered by its lack of ...
Mohammed Moudjou, Pierre Sibille, Guillaume Fichet, Fabienne Reine, Jérôme Chapuis, Laetitia Herzog, Emilie Jaumain, Florent Laferrière, Charles-Adrien Richard, Hubert Laude, Olivier Andréoletti, Human Rezaei, Vincent Béringue   +12 more
doaj   +1 more source

Immunologie und Fertilität

Journal für Gynäkologische Endokrinologie/Österreich, 2018
K.Mayer-Pickel. Frauen mit einem aktiven Lupus bzw. bei Einnahme teratogener Medikamente sollten über die Notwendigkeit einer Verhütung aufgeklärt werden. Die Auswahl der kontrazeptiven Maßnahme ist von verschiedenen Faktoren bzw.
A. Tramontana, K. Mayer-Pickel
semanticscholar   +1 more source

Between Guidelines and Daily Practice: The Persistent Use of Parenteral Depot Corticosteroids in Germany

Clinical and Translational Allergy, Volume 16, Issue 7, July 2026.
ABSTRACT Background Parenteral depot corticosteroids (PDCs) continue to be prescribed for allergic and respiratory diseases, despite clear guideline recommendations against their use. This clinical practice raises significant safety concerns. We analyzed current PDC use in Germany and characterized prescribing patterns.
Christian Taube, Timm Greulich, Sebastian Böing, Oliver Pfaar, Martin Wagenmann, Sven Becker, Mathias Sulk, Niklas J. Gerkau, Jan Claudius Schwitalla, Tim Vierbuchen   +9 more
wiley   +1 more source

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

Frontiers in Immunology, 2017
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response.
Christelle Langevin, Elina Aleksejeva, Armel Houel, Valérie Briolat, Valérie Briolat, Corinne Torhy, Aurélie Lunazzi, Jean-Pierre Levraud, Jean-Pierre Levraud, Pierre Boudinot   +9 more
doaj   +1 more source

Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase

Clinical and Developmental Immunology, 2012
Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with fibrosis and a prominent inflammatory infiltrate in the desmoplastic stroma. Moreover, in PDAC, an epithelial-to-mesenchymal transition (EMT) is observed.
Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida   +6 more
doaj   +1 more source

The carRS-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems

Scientific Reports
Antimicrobial peptides are small cationic molecules produced by eukaryotic cells to combat infection, as well as by bacteria for niche competition. Polymyxin B (PmB), a cyclic antimicrobial peptide, is used prophylactically in livestock and as a last ...
Annabelle Mathieu-Denoncourt, Gregory B Whitfield, Antony T Vincent, Cécile Berne, Julien Pauzé-Foixet, Feriel C Mahieddine, Yves V Brun, Marylise Duperthuy   +7 more
doaj   +1 more source

Characterization and effective expansion of CD4−CD8− TCRαβ+ T cells from individuals living with type 1 diabetes

Molecular Therapy: Methods & Clinical Development
CD4−CD8− TCRαβ+ (double-negative [DN]) T cells represent a rare T cell population that promotes immunological tolerance through various cytotoxic mechanisms.
J. Ernesto Fajardo-Despaigne, Félix Lombard-Vadnais, Adam-Nicolas Pelletier, Aïnhoa Olazabal, Lucie Boutin, Sarah Pasquin, Valérie Janelle, Laurent Legault, Jean-Sébastien Delisle, Erin E. Hillhouse, Lise Coderre, Sylvie Lesage   +11 more
doaj   +1 more source

Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis

Cell Communication and Signaling, 2018
Background Notch signaling controls many cellular processes, including cell fate determination, cell differentiation, proliferation and apoptosis. In mammals, four Notch receptors (Notch 1–4) can interact with five distinct ligands [Jagged1, Jagged2 ...
Sylvain Pagie, Nathalie Gérard, Béatrice Charreau   +2 more
doaj   +1 more source

Paediatric‐onset autoimmune cytopenia: How can we reduce the long‐term mortality?

British Journal of Haematology, Volume 209, Issue 2, Page 825-829, August 2026.
Nathalie Aladjidi, Thierry Leblanc, Helder Fernandes, Capucine Picard, Jacinta Bustamante, Frédéric Rieux‐Laucat, Mathieu Fusaro, Maud Tusseau, Charlotte Durand‐Teyssier, Emma Cohendy, Jérôme Granel, Stéphane Ducassou, Agathe Escudier, Despina Moshous, Marc Michel, Bertrand Godeau, Sébastien Héritier, Mony Fahd, Brigitte Bader‐Meunier, Alain Fischer, Guy Leverger, All collaborators from the French Paediatric Haemato‐Immunologic CEREVANCE Network   +21 more
wiley   +1 more source

Approche immunochimique de la structure de la protéine cellulaire PrPc ovine. Caractérisation d’anticorps discriminant les glycoformes et les allèles de la protéine Prion chez le mouton

INRAE Productions Animales, 2004
Les Encéphalopathies Spongiformes Transmissibles (EST) sont des maladies neurodégénératives caractérisées par l’accumulation dans le cerveau d’une forme anormale de la protéine prion, la PrP.
M. MOUDJOU, E. SABUNCU, D. VILETTE, A. LEDUR, H. LAUDE   +4 more
doaj   +1 more source