Results 61 to 70 of about 29,707 (208)

Frequency analysis of cytolytic T cell precursors (CTL-P) generated in vivo during lethal rabies infection of mice. I. Distinction of CTL-P with different interleukin 2 sensitivity [PDF]

, 1982
The aim of this study was to determine the number and state of activity of cytolytic T lymphocytes (CTL) and their precursors (CTL-P) present in vivo during the early stages of viral infection. The local response to lethal infection with rabies virus was
Cerottini, Fischer Lindahl, Gillis, Hardt, Komatsu, Koszinowski, Lagrange, Lefkovits, Miller, Plate, Ryser, Schneider, Skinner, Smith, Smith, Teh, Wagner, Wagner, Wiktor, Wiktor, Wiktor, Zinkernagel   +21 more
core   +1 more source

Increased intervals in enzyme replacement therapy for stable type 1 Gaucher disease: A non‐inferiority sequential trial emulation

Journal of Internal Medicine, Volume 299, Issue 5, Page 604-614, May 2026.
Abstract Objective To compare the efficacy and safety of extended interval (Q3–4W) enzyme replacement therapy (ERT) versus standard biweekly (Q2W) ERT in clinically stable type 1 Gaucher disease (GD) patients. Methods We emulated a target trial with a sequential trial design, using data from the French Gaucher Disease Registry.
Maxime Beydon, Jérôme Stirnemann, Karima Yousfi, Samira Zebiche, Dalil Hamroun, Anaïs Brassier, Samia Pichard, Laure Swiader, Thierry Billette de Villemeur, Bénédicte Héron, Florence Dalbies, Bérengère Cador, Anne‐Sophie Guemann, Francis Gaches, Bénédicte Hivert, Vanessa Leguy‐Seguin, Agathe Masseau, Yves‐Marie Pers, Magali Pettazzoni, Soumeya Bekri, Catherine Caillaud, Edouard Le Guillou, Marie Szymanowski, Leonardo Astudillo, Wladimir Mauhin, Yann Nadjar, Christine Serratrice, Marc G. Berger, Fabrice Camou, Nadia Belmatoug, Yann Nguyen, the French Evaluation of Gaucher Disease Treatment Committee   +31 more
wiley   +1 more source

Autologous Stem Cell Transplantation in Common Variable Immunodeficiency: A Case of Successful Treatment of Severe Refractory Autoimmune Encephalitis

Frontiers in Immunology, 2020
Common variable immunodeficiency (CVID) is the most common primary immunodeficiency in adults. It is associated with hypogammaglobulinemia, recurring infections and autoimmune phenomena.
Matthias Froehlich, Eva C. Schwaneck, Michael Gernert, Ottar Gadeholt, Patrick-Pascal Strunz, Henner Morbach, Hans-Peter Tony, Marc Schmalzing   +7 more
doaj   +1 more source

Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]

, 1981
Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona, B Benacerraf, CG Orosz, DH Boldt, DL Peavy, FM Rollwagen, H Lis, IFC McKenzie, J Moss, JE Geltosky, K Eichmann, LA Herzenberg, LB Grabel, LM Nadler, Michael Kramer, RE Rocklin, RM Ferguson, RW Dutton, SH Barondes, T Tada, U Koszinowski, Ulrich H. Koszinowski, VT Marchesi   +22 more
core   +1 more source

Disparition sérique et excrétion urinaire de la sulfaméthoxypyridazine chez la chèvre

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
La pharmacocinétique et l'excrétion urinaire de la sulfaméthoxypyridazine ont été déterminées sur des chèvres après une injection unique par voie intraveineuse à la dose de 100 mg/kg de poids vif.
K. Garg Satish, R.P. Uppal, J.E. Rivière   +2 more
doaj   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Beyond miRNA Cargo Profiles: Anti‐Inflammatory Roles of Extracellular Vesicle‐Enriched miRNAs Derived From Human Intervertebral Disc Cells Unveiled by Functional Testing

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Intervertebral disc (IVD) degeneration is a leading cause of chronic low back pain and a major contributor to global disability. Understanding the molecular mechanisms underlying this condition is essential for developing targeted therapies. Among these mechanisms, microRNAs (miRNAs) have emerged as critical post‐transcriptional regulators of ...
Li Li, Aiwei Sun, Saber Ghazizadeh, Hadil Al‐Jallad, Kirby Upshaw, Saleh Alfaisali, Jean Ouellet, Peter Jarzem, Hosni Cherif, Lisbet Haglund   +9 more
wiley   +1 more source

Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM [PDF]

, 2004
The surface topography of red blood cells (RBCs) was investigated under nearphysiological conditions using atomic force microscopy (AFM). An immobilization protocol was established where RBCs are coupled via molecular bonds of the membrane glycoproteins ...
Berg, Jörg, Ebner, A., Gruber, Hermann J., Hinterdorfer, Peter, Huss, Ralf, Kamruzzahan, A. S. M., Kienberger, Ferry, Rankl, Christian, Stroh, Cordula M., Zhu, Rong   +9 more
core   +1 more source

Les techniques de diagnostic en santé des espèces aquacoles : intérêt et limites

INRAE Productions Animales, 2007
Les agents pathogènes présents dans les milieux aquatiques peuvent exercer leurs méfaits dans tous les types d’élevage et sur toutes sortes d’espèces vertébrées ou invertébrées.
C. MICHEL, J.F. BERNARDET, J. CASTRIC, J.P. JOLY   +3 more
doaj   +1 more source

Autoantikörpernachweis mittels indirekter Immunfluoreszenz an HEp-2-Zellen [PDF]

, 2012
Systemic autoimmune diseases are characterized by the presence of antinuclear autoantibodies (ANAs). Diluted patient sera are typically used to screen for the presence of ANAs by immunofluorescence microscopy with fixed HEp-2 cells.
Conrad, Karsten, Csernok, Elena, Frank, Ingrid, Hiepe, Falk, Krieger, Thorsten, Kromminga, Arno, Landenberg, Philipp von, Messer, Gerald, Mierau, Rudolf, Sack, Ulrich, Witte, Torsten   +10 more
core   +1 more source