Results 81 to 90 of about 29,707 (208)

Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase

Clinical and Developmental Immunology, 2012
Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with fibrosis and a prominent inflammatory infiltrate in the desmoplastic stroma. Moreover, in PDAC, an epithelial-to-mesenchymal transition (EMT) is observed.
Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida   +6 more
doaj   +1 more source

Wenn Zellen zu Medikamenten werden : neue Zelltherapien verbessern die Heilungschancen bei Leukämien [PDF]

, 2013
Die Transplantation von Zellen aus dem Knochenmark oder von Stammzellen aus dem Blut gehört zu den bekanntesten Therapien bei Leukämie. Doch dabei treten Immunreaktionen als Nebenwirkung auf.
Bader, Peter, Ullrich, Evelyn
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Bibliographie sélective pour la traduction des sciences biomédicales [PDF]

, 2001
Département de linguistique et de ...
Vandaele, Sylvie
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Immunotherapy of lung cancer: An update [PDF]

, 2006
In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced ...
Aman MJ, Anthony HM, Atanackovic D, Bast RC, Bermers AJA, Carbone FR, Chan B, Cohen MH, Dickler M, Dranoff G, Dudley ME, Faradji A, Gotoh K, Grant SC, Kimura H, Kimura Y, Korkolopoulou P, Kradin RL, Krug LM, Krug LM, Liu M, Ma J, Marshall JL, Melioli G, Millar JW, Nemunaitis J, Nikitina E, O'Brien ME, Palmer M, Raez LE, Ratto GB, Salgia R, Smith A, Sterman D, Swisher S, Villalona-Calero MA, Yano T   +36 more
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The carRS-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems

Scientific Reports
Antimicrobial peptides are small cationic molecules produced by eukaryotic cells to combat infection, as well as by bacteria for niche competition. Polymyxin B (PmB), a cyclic antimicrobial peptide, is used prophylactically in livestock and as a last ...
Annabelle Mathieu-Denoncourt, Gregory B Whitfield, Antony T Vincent, Cécile Berne, Julien Pauzé-Foixet, Feriel C Mahieddine, Yves V Brun, Marylise Duperthuy   +7 more
doaj   +1 more source

Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis

Cell Communication and Signaling, 2018
Background Notch signaling controls many cellular processes, including cell fate determination, cell differentiation, proliferation and apoptosis. In mammals, four Notch receptors (Notch 1–4) can interact with five distinct ligands [Jagged1, Jagged2 ...
Sylvain Pagie, Nathalie Gérard, Béatrice Charreau   +2 more
doaj   +1 more source

Spatiotemporal visualization of subcellular dynamics of carbon nanotubes [PDF]

, 2012
To date, there is no consensus on the relationship between the physicochemical characteristics of carbon nanotubes (CNTs) and their biological behavior; however, there is growing evidence that the versatile characteristics make their biological fate ...
Baba, Yoshinobu, Bianco, Alberto, Braeckmans, Kevin, Habuchi, Satoshi, Kaji, Noritada, Serag, Maged F   +5 more
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Approche immunochimique de la structure de la protéine cellulaire PrPc ovine. Caractérisation d’anticorps discriminant les glycoformes et les allèles de la protéine Prion chez le mouton

INRAE Productions Animales, 2004
Les Encéphalopathies Spongiformes Transmissibles (EST) sont des maladies neurodégénératives caractérisées par l’accumulation dans le cerveau d’une forme anormale de la protéine prion, la PrP.
M. MOUDJOU, E. SABUNCU, D. VILETTE, A. LEDUR, H. LAUDE   +4 more
doaj   +1 more source

Divergent prion strain evolution driven by PrPC expression level in transgenic mice

Nature Communications, 2017
PrPC protein plays a key role in prion transmission across species. Here, the authors compare transmission of a representative scrapie isolate to transgenic mice expressing variable levels of the same Prnp allele as the donor sheep, and find divergent ...
Annick Le Dur, Thanh Lan Laï, Marie-George Stinnakre, Aude Laisné, Nathalie Chenais, Sabine Rakotobe, Bruno Passet, Fabienne Reine, Solange Soulier, Laetitia Herzog, Gaëlle Tilly, Human Rézaei, Vincent Béringue, Jean-Luc Vilotte, Hubert Laude   +14 more
doaj   +1 more source

Klinische virologie: omzien naar de toekomst [PDF]

, 2008
Edward Jenner deed eind achttiende eeuw de waarneming dat melkmeisjes, die met koepokken (vaccinia) in aanraking waren geweest, beschermd waren tegen pokken (variola).
Doornum, G.J.J. (Gerard) van
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