Results 71 to 80 of about 4,425 (147)

Divergent prion strain evolution driven by PrPC expression level in transgenic mice

Nature Communications, 2017
PrPC protein plays a key role in prion transmission across species. Here, the authors compare transmission of a representative scrapie isolate to transgenic mice expressing variable levels of the same Prnp allele as the donor sheep, and find divergent ...
Annick Le Dur, Thanh Lan Laï, Marie-George Stinnakre, Aude Laisné, Nathalie Chenais, Sabine Rakotobe, Bruno Passet, Fabienne Reine, Solange Soulier, Laetitia Herzog, Gaëlle Tilly, Human Rézaei, Vincent Béringue, Jean-Luc Vilotte, Hubert Laude   +14 more
doaj   +1 more source

The HmrABCX pathway regulates the transition between motile and sessile lifestyles in Caulobacter crescentus by a mechanism independent of hfiA transcription

mBio
During its cell cycle, the bacterium Caulobacter crescentus switches from a motile, free-living state, to a sessile surface-attached cell. During this coordinated process, cells undergo irreversible morphological changes, such as shedding of their polar ...
Sébastien Zappa, Cécile Berne, Robert I. Morton III, Gregory B. Whitfield, Jonathan De Stercke, Yves V. Brun   +5 more
doaj   +1 more source

P589: AGE AND AGE-ADAPTED RISK FACTORS HIGHLY INFLUENCE SURVIVAL PROBABILITY IN AML PATIENTS – A RETROSPECTIVE ANALYSIS

HemaSphere, 2022
K. Nachtkamp, C. Zahner, A. Fricke, T. Ulrych, F. I. Schulz, A. Kündgen, P. S. Jäger, G. Kobbe, U. Germing   +8 more
doaj   +1 more source

Phenotypic plasticity in cell elongation among closely related bacterial species

Nature Communications
Cell elongation in bacteria has been studied over many decades, in part because its underlying mechanisms are targets of numerous antibiotics. While multiple elongation modes have been described, little is known about how these strategies vary across ...
Marie Delaby, Liu Yang, Maxime Jacq, Kelley A. Gallagher, David T. Kysela, Velocity Hughes, Francisco Pulido, Frederic J. Veyrier, Michael S. VanNieuwenhze, Yves V. Brun   +9 more
doaj   +1 more source

Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells

eLife
Precision gene editing in primary hematopoietic stem and progenitor cells (HSPCs) would facilitate both curative treatments for monogenic disorders as well as disease modelling.
Fanny-Mei Cloarec-Ung, Jamie Beaulieu, Arunan Suthananthan, Bernhard Lehnertz, Guy Sauvageau, Hilary M Sheppard, David JHF Knapp   +6 more
doaj   +1 more source

In silico reconstruction of a salmonid alphavirus virion reveals distinctive molecular features implicated in virulence

iScience
Summary: Salmonid alphavirus (SAV) poses a significant disease threat to aquaculture. Recently, new alphaviruses from several fish species have been discovered. However, little is known about their biology and pathogenicity.
Stéphane Biacchesi, Calvin Fauvet, Emilie Mérour, Julie Bernard, Annie Lamoureux, Delphine Lallias, Jean K. Millet   +6 more
doaj   +1 more source

Immunologie

Springer Reference Medizin, 2020
Helga Peter, T. Penzel
semanticscholar   +1 more source

Klebsiella pneumoniae necrotizing fasciitis of the leg in an elderly French woman

Clinical Interventions in Aging, 2014
Marguerite Monié,1 Laurence Drieux,2–4 Bernadette Nzili,1 Michèle Dicko,5 Catherine Goursot,1 Sandrine Greffard,6 Dominique Decré,3,4,7 Anthony Mézière1 1Assistance Publique-Hôpitaux de Paris (AP-HP), GHU ...
Monié M, Drieux L, Nzili B, Dicko M, Goursot C, Greffard S, Decré D, Mézière A   +7 more
doaj  

Allergologie und Immunologie: Ein Hauch von «Ewigkeit» durch temporäre Tattoos

, 2018
A. Bircher
semanticscholar   +1 more source

Antigenfunktion und Molekularstruktur

CHIMIA, 1970
C.H. Schneider, A.L. de Weck
doaj   +1 more source