Results 181 to 190 of about 137,143 (306)

Harnessing Cellular Feeling: Epigenetic to Mechanical Memory as a Framework for Stem Cell Manufacturing

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stem cell‐based therapies hold transformative potential for regenerative medicine, yet their progress is constrained by persistent variability in manufacturing and clinical performance. Conventional frameworks such as Quality by Design (QbD), though effective for drugs and biologics, struggle to accommodate the dynamic nature of living cell ...
Mee‐Hae Kim, Masahiro Kino‐oka
wiley   +1 more source

Effects of preoperative recombinant Interleukin 2-based immunomodulation on outcome after gastrointestinal cancer surgery: a systematic review and meta-analysis. [PDF]

Br J Cancer
Horcicka A, Bewersdorf N, Kalkum E, Zimmermann S, Grüßer L, Dehne S, Weigand MA, Klotz R, Larmann J.   +8 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

AI-enabled photoresponsive nanoplatforms for coordinated osteosarcoma therapy and bone regeneration. [PDF]

Front Bioeng Biotechnol
Li Q, Duan S, Zhang M.
europepmc   +1 more source

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

Frontiers in Molecular Neuroscience
Basharat Hussain, Basharat Hussain, Cheng Fang, Xiaowen Huang, Ziying Feng, Ziying Feng, Yuxuan Yao, Yu Wang, Junlei Chang   +8 more
doaj   +1 more source

Therapeutic Immunomodulation in Cardiovascular Disease: Anti-inflammatory Strategies and Landmark Trials. [PDF]

Cureus
Awais M, Baroudi M, Mankani MH, Ali A, Khokhar ME, Shaukat N, Haider SU, Zafar AA, Marquez Roa LA.   +8 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Retraction of Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. [PDF]

J Clin Invest
Yang J, Jiang Z, Fitzgerald DC, Ma C, Yu S, Li H, Zhao Z, Li Y, Ciric B, Curtis M, Rostami A, Zhang GX.   +11 more
europepmc   +1 more source

Three years of follow-up bone marrow-augmented organ transplant recipients: The impact on donor-specific immune modulation [PDF]

, 1997
Banas, R, Bentlejewski, C, Corry, R, Dodson, F, Egidi, F, Fontes, P, Fung, JJ, Griffith, B, Iyengar, A, Jordan, M, Keenan, R, Pavlick, M, Pham, S, Rao, AS, Shapiro, R, Spichty, K, Starzl, TE, Zeevi, A   +17 more
core   +1 more source