Results 191 to 200 of about 48,894 (301)
Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease
Alimentary Pharmacology &Therapeutics, EarlyView.In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.Ana Garre, Andrea Nuñez Ortiz, Saioa Rubio, María Teresa Diz‐Lois Palomares, Sabino Riestra, Horacio Alonso‐Galán, Estela Fernández‐Salgado, Rocío Ferreiro‐Iglesias, Milagros Vela, Ángel Ponferrada Díaz, Eugenia Sánchez Rodríguez, Vicent Hernández, Lara Arias García, Jesús Barrio, José María Huguet, Daniel Ginard, Montserrat Rivero, Isabel Vera, Inmaculada Alonso‐Abreu, José Manuel Benítez, Mariam Aguas, Iago Rodríguez‐Lago, Xavier Calvet, Luis Fernández‐Salazar, Ana Echarri, María Teresa Arroyo, Mercè Navarro‐Llavat, Pablo Vega, Mónica Sierra, Elena Guerra del Río, Raquel Vicente, María José Casanova, Pablo Navarro, Jone Ortiz de Zarate, Pilar Varela Trastoy, Katerina Spicakova, Ana Gutiérrez, María Dolores Martín‐Arranz, Concepción Piñero, Álvaro Hernández‐Martínez, Emilio Torrella Cortés, José Miguel Marrero, Rufo H. Lorente Poyatos, Lidia Martí Romero, Orencio Bosch, José María Duque, Montserrat Aceituno, Hipólito Fernández, Belén Crespo Suarez, Ana María Fuentes Coronel, Liliana Pozzati, Pilar Robledo, Eva Sesé Abizanda, Belén Herreros Martínez, Nuria Jiménez, Pilar López Serrano, Manuela Josefa Sampedro, Fernando Bermejo, Alfredo J. Lucendo, Margarita Muñoz Vicente, Margarita Menacho, José Joaquín Ramírez Palanca, Raquel Camargo, Amalia Carmona, Sandra Torra Alsina, Margalida Calafat, José Luis F. Forcelledo, Juan Nerín de la Puerta, Isabel Nicolás, Verónica Opio, Yolanda Ber, Abdel Bouhmidi, Alfredo Abraldes Bechiarelli, Carlos Castaño‐Milla, Noelia Cruz, Jordi Gordillo, Amparo Sapiña, Alina López, Silvia Rodríguez Mondéjar, María Teresa Novella Durán, Belén Botella, Marcos Kutz, Lilyan Kolle, Ignacio Marín‐Jiménez, Francisco J. Martínez‐Cerezo, Rebeca Irisarri, Eduardo Iyo, Óscar Roncero, Miriam Sabat, Yolanda Torres Domínguez, Cesar Ledezma, Eva María Zapata, María José Alcalá, Laia Lluis, Cristina Martínez Pascual, Isabel Blázquez Gómez, Luis Hernández, Laura Mata, Ana Monrobel, Alejandro Hernández Camba, Nuria Maroto, María Tejada, María Luisa Galve, María Montealegre, Daniel Hervías, Marta Soler, José Antonio Gómez‐Valero, Manuel Barreiro‐de Acosta, Pilar Soto Escribano, José Luis Cabriada, Daniel Ceballos, Maria Esteve, Alba García Rodríguez, Vanesa Royo, Fernando Gomollón, Cristina Verdejo Gil, Pilar Nos, Ruth de Francisco, María José García, Carmen Dueñas Sadornil, Cristina Rodríguez, Beatriz Sicilia, Borja M. Fernandez‐Felix, Javier P. Gisbert, María Chaparro, on behalf of the EpidemIBD Group of GETECCU, Alfredo Abraldes Bechiarelli, José Manuel Benítez, María del Rosario Calderón, Raquel Camargo, Álvaro Hernández‐Martínez, Eva Iglesias Flores, Eduardo Leo Carnerero, Sandra Marín Pedrosa, Ana Monrobel, Andrea Núñez Ortiz, Natalia Ruiz Santana, María Tejada, Yolanda Torres Domínguez, María José Alcalá, Erika Alfambra, Yolanda Ber, Fernando Gomollón, Miguel Montoro, Juan Manuel Nerín, Elena Peña, Raquel Vicente, José María Duque, Ruth de Francisco, Alejo Mancebo Mata, Susana Martínez González, Isabel Pérez Martínez, Sabino Riestra, Pilar Varela Trastoy, Inmaculada Alonso‐Abreu, Daniel Ceballos, Noelia Cruz, Elena Guerra del Río, Alejandro Hernández Camba, Lilian Kole, José Miguel Marrero, Nuria Pérez, Marta Soler, Milagros Vela, José Luis F Forcelledo, Montserrat Rivero, Rufo Lorente Poyatos, Cristina Verdejo Gil, María Montealegre, Alfredo J Lucendo, Óscar Roncero, Abdel Bouhmidi, Daniel Hervías, Lara Arias García, Jesús Barrio, Ana Y Carbajo, Luis Fernández‐Salazar, Paola Fradejas, Ana María Fuentes Coronel, Luis Hernández, Carmen López Ramos, Laura Mata, Concepción Piñero, Beatriz Sicilia, Mónica Sierra, Mónica Vásquez, Montserrat Aceituno, Michelle Bautista, Xavier Calvet, Maria Esteve Comas, Antonia Montserrat, José Antonio Gómez Valero, Jordi Gordillo, Cesar Ledezma, Laia Lluis, Francisco J. Martínez‐Cerezo, Margarita Menacho, Mercè Navarro‐Llavat, Silvia Rodríguez Mondéjar, Miriam Sabat, Manuela Josefa Sampedro, Eva Sesé Abizanda, Anibal Silva, Sandra Torra Alsina, Leyanira Torrealba, Carmen Vila Lolo, Marta Ágreda Chinea, Alicia Algaba, Fernando Bermejo, Isabel Blázquez Gómez, Orencio Bosch, Belén Botella, María José Casanova, Carlos Castaño‐Milla, María Chaparro, Rocío De Lucas, Mercedes Domínguez‐Antonaya, María G Donday, Almudena Durán, María Luisa Galve, Laura García Ramírez, Ana Garre, Javier P. Gisbert, Iván Guerra, Paloma Jiménez, Beatriz López Cauce, Antonio López‐Sanromán, Pilar López Serrano, Ignacio Marín‐Jiménez, María Dolores Martín‐Arranz, José Antonio Olmos Jerez, Verónica Opio, José Lázaro Pérez Calle, Rocío Plaza Santos, Ángel Ponferrada Díaz, Elena San Miguel, Eugenia Sánchez Rodríguez, Isabel Vera‐Mendoza, Mariam Aguas, Marífé García‐Sepulcre, Ana Gutiérrez, Belén Herreros Martínez, José María Huguet, Nuria Jiménez, Nuria Maroto, Lidia Martí Romero, Miguel Mínguez, Margarita Muñoz Vicente, Pablo Navarro, Pilar Nos, José Joaquín Ramírez Palanca, Marisa Roldán Lafuente, Liliana Pozzati, Pilar Robledo, Manuel Barreiro‐de Acosta, Iria Bastón –Rey, Amalia Carmona, Daniel Carpio, Elena Castro, Belén Crespo Suarez, María Teresa Diz‐Lois Palomares, Ana Echarri, Jesús Daniel Fernández‐de Castro, Estela Fernández Salgado, Rocío Ferreiro‐Iglesias, Vicent Hernández, Alina López Baz, Pablo Pérez Galindo, María Jesús Ruiz Barcia, Pablo Vega, Margalida Calafat, Daniel Ginard, Eduardo Iyo, María Teresa Novella Durán, Josep Reyes, Carolina Rodríguez Hidalgo, Vanesa Royo, Amparo Sapiña.r, Ana Belen Aliende, Hipólito Fernández Rosáenz, María Fraile González, Alba García Rodríguez, Berta Lapeña Muñoz, María Teresa Moyano, Susana Revuelta Martínez, Rebeca Irisarri, Marcos Kutz, Óscar Nantes, Cristina Rodríguez, Saioa Rubio, Miren Vicuña, Horacio Alonso, Jose Luis Cabriada, Agustin Castiella Eguzkiza, Itziar Galdona, Ainara Maíz, Ana Isabel Muñagorri Santos, Nerea Muro Carral, Jone Ortiz de Zarate, Nora Otegui, Iago Rodríguez‐Lago, Katerina Spicakova, Eva María Zapata, Leire Zubiaurre Lizarralde, Jose Manuel Castillo Espinosa, María del Carmen Martínez Bonil, Cristina Martínez Pascual, Isabel Nicolás, Emilio Torrella Cortés +308 morewiley +1 more sourceTherapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract
Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang +6 morewiley +1 more sourceThe Role of IGF2BP3‐Mediated Immune Response Activation in Enhancing Immunotherapy of Koumine for Gastric Cancer
Cancer Science, EarlyView.Koumine binds IGF2BP3 and promotes its proteasomal degradation, reducing m6A on EED mRNA, accelerating EED decay, lowering H3K27me3, and promoting IRF transcription, thereby restoring MHC‐I and enhancing CD8+ T cell killing. ABSTRACT
Resistance to immune checkpoint blockade in gastric cancer often arises from defective antigen presentation due to MHC‐I Qiu Hongqiang, Lin Hailing, Lou Luqi, Wang Linyao, Lin Tian, Shengjie Zhu, Zhang Dongmei, Chen Rong, Mao Yunyi, Wancai Que, Yu Cheng +10 morewiley +1 more source
