Results 1 to 10 of about 44,987 (258)

Histologic-Based Tumor-Associated Immune Cells Status in Clear Cell Renal Cell Carcinoma Correlates with Gene Signatures Related to Cancer Immunity and Clinical Outcomes

open access: yesBiomedicines, 2022
The three-tier immunophenotype (desert, excluded, and inflamed) and the four-tier immunophenotype (cold, immunosuppressed, excluded, and hot) have been linked to prognosis and immunotherapy response.
Chisato Ohe   +12 more
doaj   +1 more source

ALK-positive Large B-cell Lymphoma: A Clinicopathologic Retrospective Descriptive Study from a Tertiary Care Cancer Centre in India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Anaplastic Lymphoma Kinase (ALK) positive Large B-Cell Lymphoma (ALK+ LBCL) is a very rare aggressive B-cell lymphoma presenting significant diagnostic challenges due to their rarity and unique immunophenotypic features.
Jayasudha Arundhathi Vasudevan   +5 more
doaj   +1 more source

Potential utility of a non-invasive menstrual blood immunophenotype analysis in reproductive medicine

open access: yesReproduction and Fertility, 2022
The purpose of this study was to determine if a comprehensive flow cytometry panel could be used to assess immunophenotype profiles in menstrual blood of patients experiencing reproductive failure and age-matched controls of proven fertility.
Kevin Marron, Conor Harrity
doaj   +1 more source

Immunophenotyping of pulmonary sarcomatoid carcinoma

open access: yesFrontiers in Immunology, 2022
BackgroundPrevious studies have suggested that patients with pulmonary sarcomatoid carcinoma (PSC)may benefit from immune checkpoint inhibitors (ICIs); however, relevant data are lacking.
Yu Ma   +6 more
doaj   +1 more source

Dysplastic transformation of plasma cell myeloma

open access: yesJournal of Applied Hematology, 2022
Rare cases of plasma cell myeloma with morphological variants have been reported. Here we report a case of a plasma cell myeloma with a very unusual presentation diagnosed based on flow cytometry, immunohistochemistry, and cytogenetic studies.
Laila Alsuhaibani, Tarek Owaidah
doaj   +1 more source

Immunological Subsets Characterization in Newly Diagnosed Relapsing–Remitting Multiple Sclerosis

open access: yesFrontiers in Immunology, 2022
ObjectivesUsing flow cytometry, we characterized myeloid, B, and T cells in patients recently diagnosed with relapsing–remitting multiple sclerosis (RRMS) naive to disease-modifying therapies (DMTs).MethodsThis prospective case–control study was ...
Emanuele D’Amico   +11 more
doaj   +1 more source

How to Diagnose and Treat CD5-Positive Lymphomas Involving the Spleen

open access: yesCurrent Oncology, 2021
Patients with CD5-expressing lymphomas presenting with splenomegaly are frequently diagnosed with chronic lymphocytic leukemia. The most important differential diagnosis is mantle cell lymphoma, both in its classical and leukemic, non-nodal forms, given ...
José Cabeçadas   +3 more
doaj   +1 more source

Immunophenotyping of Peripheral Blood Mononuclear Cells in Septic Shock Patients With High-Dimensional Flow Cytometry Analysis Reveals Two Subgroups With Differential Responses to Immunostimulant Drugs

open access: yesFrontiers in Immunology, 2021
Sepsis is associated with a dysregulated inflammatory response to infection. Despite the activation of inflammation, an immune suppression is often observed, predisposing patients to secondary infections. Therapies directed at restoration of immunity may
Ya Wang   +18 more
doaj   +1 more source

Insights from a Case of Good’s Syndrome (Immunodeficiency with Thymoma)

open access: yesBiomedicines, 2023
Immunodeficiency with thymoma was described by R.A. Good in 1954 and is also named after him. The syndrome is characterized by hypogammaglobulinemia associated with thymoma and recurrent infections, bacterial but also viral, fungal and parasitic ...
Roberto Paganelli   +6 more
doaj   +1 more source

MODERN CONCEPTS OF CHILDHOOD NON-HODGKIN LYMPHOMA [PDF]

open access: yesRomanian Journal of Pediatrics, 2008
The lymphomas are malignant transformations which can occur in any of the morphologically and functionally distinct subpopulations of lymphoid cells of the immune system and in any of the central or peripheral lymphoid organs, which accounts for the ...
Adriana Sărsan, Constantin Arion
doaj   +1 more source

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