Results 41 to 50 of about 44,987 (258)

Supplementary Figure 1 from A Leukemia-Associated CD34/CD123/CD25/CD99⁺ Immunophenotype Identifies FLT3-Mutated Clones in Acute Myeloid Leukemia

, 2015
Supplementary Figure 1. ROC curve analysis using CD34CD123CD25+ve immunophenotype.
Serena Lavorgna (14996457), Francesco Buccisano (11953685), Giovanna Borsellino (262881), Luca Battistini (262883), Giorgio Bernardi (24904), Sergio Amadori (13541), Mariadomenica Divona (12960080), Francesco Lo-Coco (481237), Daniela F. Angelini (9945440), Maria Irno Consalvo (14996463), Luca Maurillo (14980876), Michela Cittadini (1544824), Tiziana Ottone (10101109), Francesca Gargano (11333907), Marco De Bardi (381099), Adriano Venditti (3436793), Gisella Guerrera (11011620), Nélida I. Noguera (14996460)   +17 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation

Frontiers in Immunology
ObjectWe aim to explore the immunomodulatory properties of T cells on different titanium nanotubes and the key immunological factors involved in this process.MethodsTranscriptome data from GEO database of healthy people and healthy implants were used to ...
Jingju Yin, Jingju Yin, Jingju Yin, Jingju Yin, Yunyang Liao, Yunyang Liao, Yunyang Liao, Yunyang Liao, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Bangwei Che, Hanghang Zhu, Hanghang Zhu, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bin Shi, Bin Shi   +20 more
doaj   +1 more source

Characteristics of Hematopoiesis in Follicular Lymphoma Patients

Клиническая онкогематология, 2020
Aim. To assess hematopoiesis in follicular lymphoma (FL) patients at different disease stages with different morphologic structures of tumor and bone marrow microenvironment. Materials & Methods. The trial included 152 FL patients treated from 2006 to
Marina Abramovna Frenkel, A. V. Mozhenkova, N. A. Kupryshina, N. A. Falaleeva, N. N. Tupitsyn   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Comparing surface immune markers in successful and non-viable ART pregnancies on the day of hCG measurement: a prospective pilot study

Reproduction and Fertility
Blood lymphocyte reference ranges in non-pregnant females are established, but changes in pregnancy are less well understood. The early identification of immunological markers that could suggest an increased risk of early pregnancy loss may allow for ...
Kevin Marron, Conor Harrity
doaj   +1 more source

Immunophenotype of lung granulomas in HIV and non-HIV associated tuberculosis

, 2014
OBJECTIVE: To describe the immunophenotype of pulmonary TB granulomas from autopsied patients with tuberculosis (TB group) and from HIV patients with tuberculosis (TB/HIV group), and to identify the Mycobacterium species using polymerase chain reaction ...
Saldiva,Paulo H.N., Pires-Neto,Ruy C., Silva,Andreia A., Graner,Edgard, Coletta,Ricardo D., Mauad,Thais, Edgard Graner, Vargas,Pablo A., Thais Mauad, Paulo H. N. Saldiva, Ruy C. Pires-Neto, Pablo A. Vargas, Andréia A. Silva, Ricardo D. Coletta   +13 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Clinical findings and immunophenotypic profile of plasma cell leukemia: a retrospective study in a comprehensive cancer center in Turkey

Medicine Science, 2021
Plasma cell leukemia (PCL) is a rare (1-2 %) aggressive plasma cell dyscrasia (PCD) with a poor prognosis and characterized by the presence of more than 20% circulating plasma cells (PCs).
Nurgul Ozcan, Semih Basci, Eda Ozcan, Mehmet Bakirtas, Mehmet Sinan Dal, Merih Kizil Cakar, Fatma Meric Yilmaz, Fevzi Altuntas   +7 more
doaj   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source