Results 61 to 70 of about 44,987 (258)
Un Caso di linfoma a grandi linfociti granulosi (LGL) in un cavallo: caratterizzazione istochimica ed immunofenotipica
= Large granular lymphoma (LGL) in a horse: histochemical and immunophenotype characterization [PDF]
, 2007 The aim of this study is to confirm lymphoma diagnosis, characterize the neoplasia immunophenotype
and observe cell typologies by histochemical ...Cossu Rocca, Paolo Alessandro, Pirino, Salvatore, Farigu, Serafina, Columbano, Nicola, Nuvoli, Sara, Rocca, Stefano, Leoni, Antonio, Antuofermo, Elisabetta, Burrai, Giovanni Pietro, Mura, Tonina +9 morecore +1 more sourceUhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease
Advanced Science, EarlyView.Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun +9 morewiley +1 more sourceAdditional file 1 of Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells
, 2020 Additional file 1. BM-MSC immunophenotype.Silvia Claros (8592570), Antonio J. Jiménez (8592579), Antonia Gutiérrez (8592573), María García-Bonilla (8592555), Manuel Cifuentes (331123), Leonor Santos-Ruíz (8592567), Kirill Shumilov (5698901), Javier Vitorica (671358), Sebastián Jiménez (4423870), María L. García-Martín (8592561), Patricia Páez-González (8592576), M. Carmen Muñoz-Hernández (8592564), Betsaida Ojeda-Pérez (8592558) +12 morecore +1 more sourceCD4 and CD8 double-negative immunophenotype of thymoma-associated lymphocytes in a dog [PDF]
, 2020 Persistent small-cell lymphocytosis in dogs with a concurrent mediastinal mass has been associated with both thymoma and small-cell lymphoma. In thymomas, neoplastic thymic epithelial cells induce overproduction and release of polyclonal lymphocytes ...Knights, Kaori, Vernau, William, Springer, Nora L, Biller, David S, Wikander, Yvonne M, Higginbotham, Mary Lynn, Coffee, Calli, Yvonne M. Wikander, Calli Coffee, Mary Lynn Higginbotham, David S. Biller, William Vernau, Kaori Knights, Nora L. Springer +13 morecore +1 more sourceSingle‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis
Advanced Science, EarlyView.CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang +13 morewiley +1 more sourceAdditional file 2 of Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells
, 2020 Additional file 2. BM-MSC immunophenotype.Silvia Claros (8592570), Antonio J. Jiménez (8592579), Antonia Gutiérrez (8592573), María García-Bonilla (8592555), Manuel Cifuentes (331123), Leonor Santos-Ruíz (8592567), Kirill Shumilov (5698901), Javier Vitorica (671358), Sebastián Jiménez (4423870), María L. García-Martín (8592561), Patricia Páez-González (8592576), M. Carmen Muñoz-Hernández (8592564), Betsaida Ojeda-Pérez (8592558) +12 morecore +1 more sourceMultifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy
Advanced Science, EarlyView.Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang +11 morewiley +1 more sourceSOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling
Advanced Science, EarlyView.SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi +10 morewiley +1 more sourceA constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer [PDF]
Fewer than 50% of metastatic deficient mismatch repair (dMMR) colorectal cancer (CRC) patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this patient population remains a pressing clinical need.Carullo, Martina, Clayton, Kalum, Cremolini, Chiara, Rodriguez-Justo, Manuel, Acha-Sagredo, Amelia, Antoniotti, Carlotta, Mishto, Michele; id_orcid, Mikolajczak, Anna, Armero, Maria, Barral, Patricia; id_orcid, Lonardi, Sara, Fontana, Elisa, Woodman, Chloé A., Rodriguez-Lopez, Maria, Ignatova, Ekaterina, Andrei, Pietro, Woodman, Chloé A, Lim, Steven, Barral, Patricia, Fourny, Constance, Connick, Emma, Smyth, Elizabeth C., Pelka, Diana, Mishto, Michele, Green, Mary, Bhardwaj, Nisha, Sosnowska, Dominika, Arnold, James N, Ciccarelli, Francesca D, Bergamo, Francesca, Smyth, Elizabeth C, Linares, Josep, Ciraci, Paolo, Afrache, Hassnae, Intini, Rossana, Taggart, Emma, Diamantis, Nikolaos, Crawford, Marg, Hobson, Philip, Nye, Emma, Arnold, James N., Moinudeen, Hafsa Kaja, Ciccarelli, Francesca D., Ciccarelli, F, Smyth E. C., Connick, E, Bergamo, F, Rodriguez-Lopez M., Fontana E., Ignatova E., Andrei, P, Acha-Sagredo, A, Lonardi S., Pelka, D, Lonardi, S, Ciraci P., Cremolini C., Taggart, E, Antoniotti C., Lim S., Diamantis N., Rodriguez-Lopez, M, Lim, S, Andrei P., Arnold, J, Pelka D., Mikolajczak A., Barral, P, Bhardwaj, N, Fourny C., Intini R., Smyth, E, Bergamo F., Armero, M, Mikolajczak, A, Sosnowska, D, Antoniotti, C, Woodman, C, Fourny, C, Nye E., Ignatova, E, Green, M, Intini, R, Clayton K., Taggart E., Hobson P., Arnold J. N., Clayton, K, Carullo, M, Linares J., Connick E., Crawford M., Woodman C. A., Moinudeen H. K., Afrache, H, Fontana, E, Armero M., Rodriguez-Justo M., Sosnowska D., Mishto M., Nye, E, Carullo M., Bhardwaj N., Acha-Sagredo A., Green M., Ciraci, P, Diamantis, N, Crawford, M, Cremolini, C, Afrache H., Mishto, M, Ciccarelli F. D., Kaja Moinudeen, H, Linares, J, Rodriguez-Justo, M, Hobson, P, Barral P. +116 morecore +3 more sources
