Results 91 to 100 of about 70,782 (340)
Arthritis &Rheumatology, EarlyView.Objective Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood disease classically attributed to innate immune cell dysregulation. This study aimed to elucidate the role of innate lymphoid cells (ILCs), including natural killer (NK) cells and helper‐ILCs (hILCs), in sJIA during clinically inactive disease (CID) through phenotypic and ...
Linda Quatrini +19 more
wiley +1 more source
eJHaemRisk stratification and treatment response evaluation are key features in acute myeloid leukemia (AML) management. Immunophenotypic and molecular approaches all rely on the detection of persisting leukemic cells by measurable residual disease techniques.
Céline Row +12 more
doaj +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein +14 more
wiley +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract The sustainable production of jojoba oil derivatives depends on research and development focused on eco‐friendly valorization processes. This study establishes optimal conditions for converting jojoba oil into jojobyl alcohols, which is a key step in realizing its economic potential.
Laura Mendoza‐García +3 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen +46 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Talquetamab is the first and only GPRC5D × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). In the phase I/II MonumenTAL‐1 study, overall response rates (ORRs) were > 66% in patients with RRMM treated with subcutaneous talquetamab at the recommended phase II doses (RP2Ds): 0.4 mg/kg weekly and 0.8 mg/kg every other week.
Jue Gong +16 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner +10 more
wiley +1 more source
Cytometry Part A, EarlyView.ABSTRACT Systemic mastocytosis (SM) is a neoplastic disease characterized by abnormal mast cell (MC) activation and proliferation. Accurate diagnosis often relies on flow cytometry to detect aberrant CD25, CD2, and CD30 expression on MCs in bone marrow (BM).
Abdulrazzaq Alheraky +6 more
wiley +1 more source
Platelets, 2018 A high proportion of patients with mucocutaneous bleeding diathesis and suspected inherited or acquired platelet disorder remain without diagnosis even after comprehensive laboratory testing.
Oliver Andres +5 more
doaj +1 more source
The immunophenotype of reed-sternberg cells. A study of 50 cases of Hodgkin' disease using fixed frozen tissues [PDF]
, 1989 Bjarni A. Agnarsson, Marshall E. Kadin
openalex +1 more source