Results 91 to 100 of about 63,836 (336)
Circulating CD8 T cells from patients with mild-to-moderate psoriasis are functionally impaired
Frontiers in ImmunologyBackgroundPsoriasis is a systemic, immune-mediated, inflammatory skin disease in which T cells have been found to play a significant role. The phenotypic and functional properties of circulating CD8 T cells in the pathogenesis of the disease are still ...
Yiqiao Chen +8 more
doaj +1 more source
EuroFlow: Resetting leukemia and lymphoma immunophenotyping. Basis for companion diagnostics and personalized medicine [PDF]
, 2016 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivative Works 3.0 Unported License.-- Editorial.We are grateful to Dr Jean-Luc Sanne of the European Commission for his support and monitoring of the EuroFlow project.Peer ...
Dongen, J. J. M. van, Orfao, Alberto
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Advanced Science, EarlyView.This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen +9 more
wiley +1 more source
Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]
, 2011 Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah +1 more
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Advanced Science, EarlyView.Precision targeting of the spleen and myeloid cells of the tumor microenvironment, with minimal hepatic delivery, is achieved using a modular peptide dendrimer‐lipid nanocarrier. Functional assays, transcriptomics, and rodent models validate this novel myeloid cell targeting nanocarrier as an efficacious immunotherapy, both as a cancer vaccine platform
Lawrence James Billing +9 more
wiley +1 more source
Chronic lymphocytic leukemia in Kenya: an immunophenotypic and clinicopathologic study [PDF]
, 2013 Objective: To define cases of chronic lymphocytic leukemia (CLL) by immunophenotypic criteria and describe the associated clinical features in patients diagnosed at Aga Khan University Hospital, Nairobi. Background: Rising to the growing cancer challenge
Mulwa-Babu, E., Paresh, D., Riyat, M.
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Spondylocostal dysostosis (SCDO) is a rare genetic disorder characterized by abnormal development of the axial skeleton, resulting in malformations of the vertebrae and ribs that often impair lung development and lead to significant respiratory morbidity.
Jonathan Rips +8 more
wiley +1 more source
B-cell Prolymphocytic Leukemia in a Young Male [PDF]
, 2011 B-cell prolymphocytic leukemia [B-PLL] is a neoplasm of B prolymphocytes affecting the peripheral blood, bone marrow and spleen. The principal disease characteristics are massive splenomegaly with absent or minimal peripheral lymphadenopathy and a ...
Fernandes, H +3 more
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