Results 161 to 170 of about 45,883 (301)

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

open access: yesThe Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov   +6 more
wiley   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

open access: yesThe Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps   +3 more
wiley   +1 more source

Mouse cell surface antigens: nomenclature and immunophenotyping.

open access: yes, 1998
This paper reviews cell surface Ags expressed on mouse hemopoietic and nonhemopoietic cells. The review will cover molecules included in the cluster of differentiation (CD) from CD1 to CD166 and lymphocyte Ag (Ly) series from Ly-1 to Ly-81 as well as ...
Maltais, L   +3 more
core  

From inflammation to neurodegeneration: an exploratory pilot study of a diagnostic framework for progression in MS. [PDF]

open access: yesFront Neurol
Hegelmaier T   +11 more
europepmc   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

open access: yesPrecision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu   +4 more
wiley   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

open access: yesRheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning   +7 more
wiley   +1 more source

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study

open access: yesRespirology, EarlyView.
We assessed the diagnostic yield of EBUS‐guided transbronchial mediastinal cryobiopsy (EBUS‐TBMC) compared with EBUS‐transbronchial needle aspiration (EBUS‐TBNA) in patients with suspected mediastinal lymphoproliferative disorders (LPDs). EBUS‐TBMC was superior to EBUS‐TBNA and achieved a high diagnostic yield in patients with suspected mediastinal ...
Yaniv Dotan   +12 more
wiley   +1 more source

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