Evaluation of specificity and sensitivity of IRT/IRT protocol in the cystic fibrosis newborn screening program: 6-year experience of three tertiary centers [PDF]
We aimed to evaluate cutoff values of immunoreactive trypsinogen (IRT)/IRT and determine relationship between IRT values and clinical characteristics of children with cystic fibrosis (CF). This study is cross-sectional study.
Budakoglu, Isil Irem +11 more
core +1 more source
Serum Immunoreactive Pancreatic Lipase and Cationic Trypsinogen for the Assessment of Exocrine Pancreatic Function in Older Patients with Cystic-Fibrosis [PDF]
Indirect and qualitative tests of pancreatic function are commonly used to screen patients with cystic fibrosis for pancreatic insufficiency. In an attempt to develop a more quantitative assessment, we compared the usefulness of measuring serum ...
Dati, F +11 more
core
Early manifestations of cystic fibrosis in a premature patient with complex meconium ileus at birth
OBJECTIVE: To report a case of a preterm infant with complex meconium ileus at birth and cystic fibrosis. CASE DESCRIPTION: A male infant was born by vaginal delivery at 33 weeks and 5 days of gestational age with respiratory distress and severe ...
Ieda Regina Lopes Del Ciampo +6 more
doaj +1 more source
A proline‐rich peptide (P6) embedded in crosslinked hyaluronic acid replicates EMD's early anti‐inflammatory and proremodelling signature in a porcine gingival model, highlighting a fully synthetic, ethically sound candidate for periodontal regeneration.
Øystein Øvrebø +12 more
wiley +1 more source
Compartmentalization of the protease-antiprotease balance in early severe acute pancreatitis. [PDF]
OBJECTIVE: To assess the balance between trypsin and protease inhibitors simultaneously in the systemic circulation and in the thoracic lymph and peritoneal exudate.
Reynaert, Marc +3 more
core +1 more source
BackgroundUniversal newborn screening changed the way medical providers think about the presentation of cystic fibrosis (CF). Before implementation of universal screening, it was common for children with CF to present with failure to thrive, nutritional ...
Annemarie G. Wolfe +8 more
doaj +1 more source
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease [PDF]
In order to investigate the role of renal factors in affecting trypsinogen 1 metabolism and excretion in chronic pancreatic disease, serum immunoreactive trypsin (IRT), urinary IRT, gamma-glutamyltransferase (GGT), alpha-glucosidase (AGL) and RNase ...
D. Basso +8 more
core +2 more sources
BackgroundSome infants undergoing newborn screening (NBS) tests have inconclusive sweat chloride test (SCT) results that lead to the designation of Cystic Fibrosis Screen Positive, Inconclusive Diagnosis/CFTR-related metabolic syndrome (CFSPID/CRMS ...
Mohini A. Gunnett +9 more
doaj +1 more source
Cystic Fibrosis Year in Review 2024
ABSTRACT In 2024, important advances for people with cystic fibrosis (CF) were published. Important guidelines for newborn screening and care of infants diagnosed with CF transmembrane conductance regulator (CFTR)‐Related Metabolic Syndrome/Cystic Fibrosis Screen Positive Inconclusive Diagnosis (CRMS/CFSPID) were published alongside related key lessons
Adrienne P. Savant
wiley +1 more source
Plasma Immunoreactive Pancreatic Cationic Trypsinogen in Cystic Fibrosis: a Sensitive Indicator of Exocrine Pancreatic Dysfunction [PDF]
Plasma immunoreactive cationic trypsin(ogen) levels were determined in 32 control subjects and 43 patients with varying degrees of pancreatic insufficiency including 35 with cystic fibrosis (CF) and eight with Shwachman's syndrome. In six CF infants less than 2 years of age, plasma trypsin(ogen) levels were significantly elevated (97.3 +/- 62.2 ng/ml ...
P R, Durie +6 more
openaire +2 more sources

