Results 101 to 110 of about 234,838 (300)

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

open access: yes, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Mann, Klaus   +4 more
core   +1 more source

Effect of digestion on the immunoreactivity and proinflammatory properties of recombinant peanut allergen Ara h 1

open access: yesFood and Agricultural Immunology, 2019
Ara h 1 is one of the major allergens existed in peanut, peptides formed in the digestion process of Ara h 1 could induce allergic symptoms and cause local inflammatory. The mechanism of intestine epithelial immune has not been clarified yet.
Yang Tian   +4 more
doaj   +1 more source

IgA anti-gliadin antibody immunoreactivity to food proteins

open access: yes, 2003
We developed a competitive enzyme-linked immunosorbent assay (cELISA) based on bread wheat flour gliadin as coated antigen and human serum IgA as primary antibody in order to quantify the immunoreactivity of untreated celiac patient IgA antigliadin ...
M.T. Bardella   +3 more
core   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

open access: yesAdvanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang   +7 more
wiley   +1 more source

Summary of α-synuclein immunoreactivity in nevi.

open access: yes, 2013
Summary of α-synuclein immunoreactivity in nevi.
Yasuhiro Matsuo (365124)   +1 more
core   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

open access: yesAdvanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae   +27 more
wiley   +1 more source

G Protein-Coupled Estrogen Receptor Immunoreactivity in the Rat Hypothalamus Is Widely Distributed in Neurons, Astrocytes, and Oligodendrocytes, Fluctuates during the Estrous Cycle, and Is Sexually Dimorphic

open access: yes, 2020
Introduction: The membrane-associated G protein-coupled estrogen receptor 1 (GPER) mediates the regulation by estradiol of arginine-vasopressin immunoreactivity in the supraoptic and paraventricular hypothalamic nuclei of female rats and is involved in ...
Collado, Paloma   +19 more
core   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang   +9 more
wiley   +1 more source

Photomicrographs showing p-SMAD1/5/8 immunoreactivity.

open access: yes, 2013
Photomicrographs showing similar p-SMAD1/5/8 immunoreactivity (brown DAB staining) in the endothelium of rat pulmonary vasculature in (A) control lung at gestation e19.5 (manification ×100) and (B) LCDH lung, at gestation e19.5 (×100).
Paul Damion Losty (325540)   +4 more
core   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

open access: yesAdvanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han   +16 more
wiley   +1 more source

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