Results 131 to 140 of about 30,806 (226)
Interpreting immunoregulation in lung fibrosis: a new branch of the immune model.
Immunostimulation is recognized as a significant contributor to lung fibrosis in certain animal models and subsets of patients. Recently, we have elucidated an additional mechanism involving the potential implication of immunoregulation during ...
Resolution of Pulmonary Fibrosis +1 more
core
Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
wiley +1 more source
Evaluation of TLR4 Gene Expression in Mustard Gas Injured Persons’ Lungs
طب جانباز, 2014 Aims: Recurrent respiratory infections are one of the clinical protests of those with delayed complications of exposure to mustard gas. Studies Show that inflammatory mediators have been changed in serum, sputum and Broncho-Alveolar Lavage (BAL) samples ...
S. Ghaffarpour +5 more
doaj
Drug Development Research, Volume 87, Issue 7, November 2026.ABSTRACT Lipopolysaccharide (LPS) induces endotoxemia‐associated inflammatory cardiac injury rather than classical viral or autoimmune myocarditis. Sphingosine‐1‐phosphate (S1P) regulates cardiovascular and immune responses, predominantly through S1P receptors, but whether it also modulates macrophage‐associated inflammatory signaling during LPS ...
Chaofu Yue +15 more
wiley +1 more source
Advanced Science, Volume 13, Issue 56, 9 October 2026.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Advanced Science, Volume 13, Issue 56, 9 October 2026.QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li +9 more
wiley +1 more source
Tolerance: two pathways of negative immunoregulation in contact sensitivity to DNFB
, 1977 ance) is an important regulatory phenomenon. After many years of investigation, it now appears that a single mechanism cannot account for all reported experiments. Among the pathways for such nega-tive immunoregulation are clone inactivation or deletion,
H. N. Claman +2 more
core
Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley +1 more source
Arthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling
Comprehensive Physiology, Volume 16, Issue 5, October 2026.Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond +6 more
wiley +1 more source