Results 21 to 30 of about 30,806 (226)

RANKL Triggers Treg-Mediated Immunoregulation in Inflammatory Osteolysis

, 2018
The chronic inflammatory immune response triggered by the infection of the tooth root canal system results in the local upregulation of RANKL, resulting in periapical bone loss. While RANKL has a well-characterized role in the control of bone homeostasis/
C.S. Sfeir, S.R. Little, A.C. Fonseca, A. Letra, A.P.F. Trombone, R.M. Silva, C.F. Francisconi, G.P. Garlet, A.E. Vieira, M.C.S. Azevedo, A.P. Tabanez   +10 more
core   +1 more source

Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation

, 2012
Major depressive disorder is a common neuropsychiatric disorder contributing to several socio-economic burdens including disability and suicide. As the underlying pathophysiology of major depressive disorder remains unclear, no objective test is yet ...
Zhang, Ru-Fang, Luo, Dan, Li, Wen-Juan, Xie, Peng, Mu, Jun, Xu, Hong-Bo, Wang, Ying, Zhang, Yukui, Zhang, Lihua, 谢鹏, Zhou, Yuan, Fang, Liang   +11 more
core   +1 more source

Immunoregulation on the Ocular Surface: 2nd Cullen Symposium

, 2009
A one-day symposium with 20 invited participants was held to review current knowledge regarding immunoregulation in the ocular surface and cornea. The program consisted of 11 lectures on various aspects of ocular and systemic immunoregulation, followed ...
Pflugfelder, Stephen C, The Symposium Participants, Stern, Michael E   +2 more
core   +1 more source

Effects of wheat peptide supplementation on anti-fatigue and immunoregulation during incremental swimming exercise in rats

, 2017
This study elucidated the effects of wheat peptide administration on anti-fatigue and immunoregulation functions in rats.
Jin Liu, Xiaoxue Yang, Zhenyu Wang, Zhiqiang Zheng, Limin Hao, Ping Qian, Shuntang Guo   +6 more
core   +1 more source

A Review in Research Progress Concerning m6A Methylation and Immunoregulation [PDF]

, 2019
Over 100 types of cellular RNA modifications have been identified in both coding and a variety of non-coding RNAs. N6-methyladenosine (m6A) is the most prevalent and abundant post-transcriptional RNA modification on eukaryote mRNA, and its biological ...
Jinrong Fu, Caiyan Zhang, Yufeng Zhou
core   +1 more source

Single-Cell Protein and RNA Expression Analysis of Mononuclear Phagocytes in Intestinal Mucosa and Mesenteric Lymph Nodes of Ulcerative Colitis and Crohn’s Disease Patients

Cells, 2020
Inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are driven by an abnormal immune response to commensal microbiota in genetically susceptible hosts.
Laurence Chapuy, Marika Sarfati
doaj   +1 more source

Quaternary Interaction of the HIV-1 Envelope Trimer with CD4 and Neutralizing Antibodies

Viruses, 2021
The entry of HIV-1 into host cells is initiated by the interaction of the viral envelope (Env) spike with the CD4 receptor. During this process, the spike undergoes a series of conformational changes that eventually lead to the exposure of the fusion ...
Qingbo Liu, Peng Zhang, Paolo Lusso
doaj   +1 more source

Immunoregulation of Glia after spinal cord injury: a bibliometric analysis [PDF]

ObjectiveImmunoregulation is a complex and critical process in the pathological process of spinal cord injury (SCI), which is regulated by various factors and plays an important role in the functional repair of SCI.
Rong Hu, Lei Wu, Yi Huang, Kelin He, Ruijie Ma   +4 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

Cell Reports, 2017
Peripheral tolerance is crucial for avoiding activation of self-reactive T cells to tissue-restricted antigens. Sterile tissue injury can break peripheral tolerance, but it is unclear how autoreactive T cells get activated in response to self. An example
Katrien Van der Borght, Charlotte L. Scott, Veronika Nindl, Ann Bouché, Liesbet Martens, Dorine Sichien, Justine Van Moorleghem, Manon Vanheerswynghels, Sofie De Prijck, Yvan Saeys, Burkhard Ludewig, Thierry Gillebert, Martin Guilliams, Peter Carmeliet, Bart N. Lambrecht   +14 more
doaj   +1 more source