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Immunosenescence and HIV

Current Opinion in Immunology, 2012
The present review discusses the interplay between HIV infection and other environmental factors (e.g. co-infection with CMV) in the acceleration of the aging process of the immune system, leading to 'immunosenescence.'Basic studies in cell biology demonstrate that replicative senescence is a common pathway of many cell lineages, including those of the
Steven G, Deeks   +2 more
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The immunosenescence.

Rivista di biologia, 2009
Aging is a post-maturational process, biologically characterized by the progressive failure to maintain or restore the physiologic homeostasis. Such a complex phenomenon is influenced by the interaction among genetic, epigenetic, environmental, behavioral and socio-economic factors and involves the whole body, including immune system.
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Immunosenescence

2013
Introduction to Ageing of the Adaptive Immune System.- The chronic stress of caregiving accelerates the natural aging of the immune system.- Stress and ageing: Effects on neutrophil function.- Stress, Aging, and Wound Healing.- Psychoneuromicrobiology: cytomegalovirus infection as a putative link between stress, aging and immunity.- Psychosocial ...
Bosch, J.A., Phillips, A.C., Lord, J.M.
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Immunosenescence: a review

Gériatrie et Psychologie Neuropsychiatrie du Viellissement, 2015
Immunosenescence is a progressive deterioration of the immune system with ageing. A multifactorial condition, including multimorbidities and environmental factors in the elderly, increases the frailty risks. Some infection and nutritional factors contribute to the onset of decline of response to infection.
Gilles, Berrut, Laure, de Decker
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Immunoproteasomes and immunosenescence

Ageing Research Reviews, 2003
Aging is a complex process which is accompanied with the decline and the reshaping of different functions of the body. In particular the immune system is characterized, during ageing (immunosenescence) by a remodeling of innate immunity (well preserved, up-regulated) and clonotypical immunity (severely altered) and by the occurrence of a chronic ...
Mishto M.   +5 more
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Immunosenescence: a review

Archives of Gerontology and Geriatrics, 2001
Aging involves the morphological and functional integrity of all organs, including the cellular and humoral immunological functions. The main alterations can be listed as follows: (i) Thymic involution resulting in the decreased number of lymphoid precursor T- and B-cells.
MALAGUARNERA, Lucia   +7 more
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Immunosenescence and infectious diseases

Microbes and Infection, 2001
Infectious diseases are major causes, with malignancies, of morbidity and mortality in the elderly. Increased susceptibility to infections may result from underlying dysfunction of an aged immune system; moreover, inappropriate immunologic functions associated with aging can determine an insufficient response to vaccines.
GINALDI, Lia   +4 more
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Immunosenescence and Anti-Immunosenescence Therapies: The Case of Probiotics

Rejuvenation Research, 2008
Aging is a complex process that negatively impacts the development of the immune system and its ability to function. Progressive changes in the T and B cell systems over the life span have a major impact on the capacity to respond to immune challenge. These cumulative age-associated changes in immune competence are termed immunosenescence. This process
CANDORE, Giuseppina   +8 more
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Innate and adaptive immunosenescence

Annals of Allergy, Asthma & Immunology, 2010
To review the effect of increasing age on the immune system and some of its clinical implications.MEDLINE and PubMed searches were performed cross-referencing the keywords immunosenescence, aging, and immunity. Articles were reviewed for additional citations.Articles were reviewed and selected based on relevance to subject matter.The study of ...
Shradha, Agarwal, Paula J, Busse
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Immunosenescence

2007
Slabljenje imunoloških funkcija u starosti naziva se starenje imunološkog sustava (engl. immunosenescence), a posljedica je procesa trajnog «remodeliranja» imunološkog odgovora tijekom života. U starijih ljudi imunološki odgovor na «poznate» antigene je održan, ali je sposobnost primarnog imunološkog odgovora na antigene s kojima se do tada nisu ...
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