Results 211 to 220 of about 61,557 (297)

Impact of belimumab on the utility of serological markers for assessing systemic lupus erythematosus activity. [PDF]

Lupus Sci Med
Moreno-Torres V, Royuela A, Policarpo-Torres G, Paredes Ruiz D, Calabuig M, Sánchez Berná I, Capdevila Pons O, Colodro A, García-Morillo JS, Pallarés L, Trapiella L, Marin Ballvé A, Lavilla-Olleros C, Callejas-Rubio JL, Tornero F, Parra S, Rodríguez-Pintó I, Barbado Ajo J, Calero-Paniagua I, Rubio E, Argibay A, Gómez-Verdú JM, López-Dupla JM, Ripper CJ, Robles-Marhuenda A, Calvo-Begueria E, Fonseca E, González-García A, López-Aldabe K, Frutos-Pérez B, Hurtado-García R, Ponce A, Artinyan G, Crisolino Pozas AP, De Miguel-Campo B, Pousibet J, Espinosa G, Autoimmune Diseases Study Group (GEAS), Spanish Society of Internal Medicine (SEMI).   +38 more
europepmc   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

High disease activity persists in adults with childhood-onset lupus. [PDF]

Lupus Sci Med
Koelmeyer R, Gregory K, Kandane-Rathnayake R, Goldblatt F, O'Neill S, Rischmueller M, Nikpour M, Hassett G, Hissaria P, Ranganathan D, Barrett C, Hennessey A, Tsai T, Gowdie P, Morand EF, Hoi A.   +15 more
europepmc   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

The impact of systemic long-term medications for the development of age-related macular degeneration. [PDF]

Acta Ophthalmol
Heloterä H, Sund R, Rikkonen T, Kaarniranta K.   +3 more
europepmc   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

Advanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang, Qian Cheng, Ziyi Wang, Jianwen Wei, Qun Guan, Huazhong Yu, Qingwen Zhang, Caixia Yin, Ruibing Wang   +8 more
wiley   +1 more source

Effectiveness of a video-based intervention in improving skin cancer risk awareness and preventative behaviors among a diverse population of solid organ transplant recipients

JAAD International
Neha Parvathala, BS, Ritika Saranath, MD, Yasaman Pedram, BS, Alison Ly, BS, Autumn Boutin, BS, Jacob Gomez, MD, Shannon Wong-Michalak, MD, Braulio Fernandez, MD, Renee Haughton, MD, Cassidy Hernandez-Tamayo, MPH, Jack Rodman, MPH, Andrew Kwong, MD, Binh Ngo, MD, Jenny Hu, MD, Iris Ahronowitz, MD   +14 more
doaj   +1 more source

Idiopathic Pulmonary Fibrosis update, comparing the Australasian Interstitial Lung Disease Registry to the Australian Idiopathic Pulmonary Fibrosis Registry. [PDF]

Intern Med J
Chee M, Khor YH, Jackson D, Cooper W, D'Costa J, de Boer S, Edwards A, Ellis S, Gabbay E, Gallagher H, Glaspole I, Goh N, Grainge C, Hopkins P, Keir G, Kwan B, Mackintosh J, Moodley Y, Moore I, Navaratnam V, Ong C, Reynolds P, Royals K, Teoh A, Troy L, Veitch E, Wilsher M, Wrobel J, Zappala C, Corte T, Thien F, AILDR Steering Committee.   +31 more
europepmc   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Tacrolimus-Induced Atypical Posterior Reversible Encephalopathy Syndrome (PRES) in a Kidney Transplant Recipient: A Case Report. [PDF]

Clin Case Rep
Sadeghnia R, Fayez SM, Samadi S.
europepmc   +1 more source