Results 81 to 90 of about 61,557 (297)

Immunosuppressant drug monitoring: Is the laboratory meeting clinical expectations?

, 2005
ObjectiveTo review the literature relating to immunosuppressant drug measurement as performed in therapeutic drug monitoring laboratories associated with transplantation centers and consider whether the assay methods widely used for patient dosage ...
Morris, R.
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Erianin inhibits proliferation of activated T cells by downregulating CyclinB1

陆军军医大学学报
Objective To investigate the inhibitory effect of erianin on T cell proliferation and its underlying mechanism. Methods Peripheral blood mononuclear cells (PBMCs) were isolated using density gradient centrifugation, and T cells were purified by ...
JING Lin, ZHANG Ting, LUO Xinyan
doaj   +1 more source

Impact of immunosuppressant therapy on new-onset diabetes in liver transplant recipients

, 2017
Fu-Chao Liu,1,2,* Huan-Tang Lin,1,2,* Jr-Rung Lin,1–3 Huang-Ping Yu1,2 1Department of Anesthesiology, Chang Gung Memorial Hospital, 2College of Medicine, 3Clinical Informatics and Medical Statistics Research Center and Graduate Institute of ...
Lin HT, Yu HP, Liu FC, Lin JR
core  

Immunosuppressant-related cancer risks in renal transplant recipients and patients with glomerular diseases

, 2023
This thesis details the study of immunosuppressant-related cancer risks in two major renal conditions required long-term immunosuppressants; renal transplant recipients (RTRs) and individuals with glomerular diseases (GD). This study was conducted in the
Thet, Zaw
core   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Erdheim Chester disease: A case with cutaneous involvement

Turkderm Turkish Archives of Dermatology and Venereology
Erdheim-Chester disease (ECD) is a rare multisystem disease characterized by the proliferation of non-Langerhans histiocytes. It is characterized by excessive production and accumulation of histiocytes in multiple tissues and organs. Sites of involvement
Sera Nur Yücesoy, Güllü Gencebay, Ayşe Mine Önenerk, Tumay Ak, Yusuf Demir, İpek Sertbudak, Övgü Aydın Ülgen, Zekayi Kutlubay   +7 more
doaj   +1 more source

Investigating barriers to immunosuppressant medication adherence in renal transplant patients

, 2017
Immunosuppressant medication non-adherence can result in allograft rejection and loss. The aim of this study was to investigate the prevalence of non-adherence and barriers to adherence with immunosuppressant medications, in an adult renal transplant ...
Campbell, Scott B., Cottrell, W. Neil, Cossart, Amelia R., Isbel, Nicole M., Staatz, Christine E.   +4 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source