Results 101 to 110 of about 392,479 (342)

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Liver transplantation immunology: Immunosuppression, rejection, and immunomodulation.

Journal of Hepatology, 2023
A. Montaño-Loza, M. Rodríguez-Perálvarez, G. Pageaux, A. Sánchez‐Fueyo, S. Feng   +4 more
semanticscholar   +1 more source

Restoration of liver function in gunn rats without immunosuppression using transplanted microencapsulated hepatocytes [PDF]

, 1990
Vivek Dixit, Ruth Darvasi, Marika Arthur, Maria Brezina, Klaus J. Lewin, Gary Gitnick   +5 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Immunosuppression variably impacts outcomes for patients hospitalized with COVID-19: A retrospective cohort study.

PLoS ONE
BackgroundAdults with immunosuppression are more likely to develop severe COVID-19 than adults without immunosuppression. Less is known about differences in outcomes for adults with immunosuppression who are hospitalized with COVID-19.MethodsA ...
Vijeeth Guggilla, Jennifer A Pacheco, Alexandre M Carvalho, Grant R Whitmer, Anna E Pawlowski, Jodi L Johnson, Catherine A Gao, Chad J Achenbach, Theresa L Walunas   +8 more
doaj   +1 more source

Pulmonary arterial hypertension in systemic lupus erythematosus may benefit by addition of immunosuppression to vasodilator therapy: an observational study [PDF]

, 2015
Sirisha Kommireddy, Srinivas Bhyravavajhala, Kishorebabu Kurimeti, Srinivasa Chennareddy, S Kanchinadham, Irlapati Rajendra Vara Prasad, Liza Rajasekhar   +6 more
openalex   +1 more source

S282: A RANDOMIZED CONTROLLED CLINICAL TRIAL DEMONSTRATES THAT PLASMA FROM CONVALESCENT AND VACCINATED DONORS IMPROVES OUTCOME OF COVID-19 IN PATIENTS WITH HEMATOLOGICAL DISEASE, CANCER OR IMMUNOSUPPRESSION

, 2022
C. Müller-Tidow, Maike Janssen, U. Schäkel, J. Gall, Albrecht Leo, P. Stelmach, Johannes Krisam, Lukas Baumann, Julia Stermann, U. Merle, Martin Zeier, M.A. Weigand, Lars Bullinger, Jens Schrezenmeier, Martin Bornhäuser, Nael Alakel, O. Witzke, Tammy Wolf, M. J. Vehreschild, Stefan Schmiedel, Marylyn M. Addo, F. Herth, M Kreutner, Phil‐Robin Tepasse, Bernd Hertenstein, Matthias Hänel, Anke Morgner, Michael Kiehl, Olaf Hopfer, M.-A. Wattad, C Schimanski, Cihan Celik, Thorsten Pohle, M. Ruhe, Werner Kern, A Schmitt, M. Schmitt, P. Dreger, H.-M. Lorenz, M. Souto-Carneiro, Neils Halama, S. Meuer, H.-G. Kräusslich, B. Müller, Ralf Bartenschlager, J. Klemmer, K. Kriegsmann, R. F. Schlenk, Claudia M. Denkinger   +48 more
openalex   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.

Cancer Cell, 2021
J. Chan, Á. Quintanal-Villalonga, Vianne R. Gao, Yubin Xie, V. Allaj, O. Chaudhary, I. Masilionis, J. Egger, A. Chow, T. Walle, M. Mattar, Dig V.K. Yarlagadda, James L. Wang, F. Uddin, M. Offin, M. Ciampricotti, Besnik Qeriqi, Amber Bahr, E. de Stanchina, U. Bhanot, W. Lai, M. Bott, David R. Jones, A. Ruiz, M. Baine, Yanyun Li, N. Rekhtman, J. Poirier, T. Nawy, T. Sen, L. Mazutis, T. Hollmann, D. Pe’er, C. Rudin   +33 more
semanticscholar   +1 more source