Results 131 to 140 of about 521,863 (391)

Alemtuzumab pre-conditioning with tacrolimus monotherapy in pediatric renal transplantation [PDF]

, 2007
We employed antibody pre-conditioning with alemtuzumab and posttransplant immunosuppression with low-dose tacrolimus monotherapy in 26 consecutive pediatric kidney transplant recipients between January 2004 and December 2005. Mean recipient age was 10.7 ±
Basu, A, Ellis, D, Erkan, E, Gray, EA, Grosso, MJ, James, G, Kayler, LK, Marcos, A, McFeaters, CG, Moritz, ML, Shapiro, R, Starzl, TE, Tan, HP, Vats, AN, Zeevi, A   +14 more
core   +1 more source

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

Advanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li, Chaochao Wang, Yelin Wu, Jiajia Zhang, Han Zhang, Shanshan Qin, Linglin Tang, Fei Yu   +7 more
wiley   +1 more source

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

New England Journal of Medicine, 2022
R. Peffault de Latour, A. Kulasekararaj, S. Iacobelli, Sofie R Terwel, Riley Cook, M. Griffin, C. Halkes, C. Récher, F. Barraco, E. Forcade, J. Vallejo, B. Drexler, J. Mear, Alexander Smith, E. Angelucci, R. Raymakers, M. D. de Groot, É. Daguindau, E. Nur, W. Barcellini, N. Russell, L. Terriou, A. Iori, Ursula La Rocca, A. Sureda, I. Sánchez-Ortega, B. Xicoy, I. Jarque, J. Cavenagh, F. Sicre de Fontbrune, S. Marotta, T. Munir, J. Tjon, S. Tavitian, A. Praire, L. Clément, F. Rabian, L. Marano, A. Hill, E. Palmisani, P. Muus, F. Cacace, Camilla Frieri, M. V. van Lint, J. Passweg, J. Marsh, G. Socié, G. Mufti, C. Dufour, A. Risitano   +49 more
semanticscholar   +1 more source

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Frontiers in Immunology, 2018
Dysregulated host immune responses to infection often occur, leading to sepsis, multiple organ failure, and death. Some patients rapidly recover from sepsis, but many develop chronic critical illness (CCI), a debilitating condition that impacts ...
Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, Hiroyuki Horiguchi, S. Brakenridge, Anna K. Gardner, P. Efron, A. Bihorac, M. Segal, F. Moore, L. Moldawer   +10 more
semanticscholar   +1 more source

Alemtuzumab preconditioning with tacrolimus monotherapy - The impact of serial monitoring for donor-specific antibody [PDF]

, 2008
BACKGROUND. Antibody preconditioning with tacrolimus monotherapy has allowed many renal allograft recipients to be maintained on spaced weaning. METHODS.
Adriana Zeevi, Alin L. Girnita, Amadeo Marcos, Amit Basu, Calne, Deanna M. Blisard, Edward A. Gray, Girnita, Henkie P. Tan, Kirk, Knechtle, Kowalski, Liise K. Kayler, Mao, Meier-Kriesche, Mizutani, Montgomery, Ngoc L. Thai, Parmjeet S. Randhawa, Pascual, Pei, Ron Shapiro, Shapiro, Shapiro, Shapiro, Starzl, Stuart, Tan, Thomas E. Starzl, Waldmann   +29 more
core   +1 more source

On‐Chip Multiplexed Voltammetry Using a Universal Antifouling Hydrogel and Porous Gold Foam Interface for Stress and Inflammation Monitoring

Advanced Sensor Research, EarlyView.
A multiplexed device is fabricated via silicon microelectronics and adapted for electrochemical sensing interface. Its 100 um gold disk electrodes are modified with porous gold foam and coated with a rapid, biocompatibleantifouling layer. Universal immunoglobulin G (IgG) capture is enabled through Protein A/G.
Vuslat B. Juska, Stacey Hendriks, Esmeralda Santillan‐Urquiza, Nadia Moukri, Pedro Estrela, Graeme D. Maxwell, Bernadette O'Brien, Bernardo Patella, Rosalinda Inguanta, Alan O'Riordan   +9 more
wiley   +1 more source

Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12 [PDF]

, 2011
Immunotherapy-based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours.
Alaniz, Almand, Appay, Barajas, Bell, Beyer, Bluestone, Brodsky, Bronte, Caruso, Catalina Atorrasagasti, Clark, Colombo, Colvin, Croci, Curiel, Dieckmann, Elkord, Ferlay, Flavia Piccioni, Gabrilovich, Gabrilovich, Ghiringhelli, Ghiringhelli, Gomez, Guillermo Mazzolini, Haigh, Huang, Jaime A. Espinoza, Jorge B. Aquino, Juan Bayo, Kerkar, Ko, Larmonier, Laura Alaniz, Leonard, Lorenz, Malvicini, Manuel Gidekel, Mariana Garcia, Mariana Ingolotti, Mariana Malvicini, Matar, Mazzolini, Mazzolini, Mazzolini, Medina-Echeverz, Melero, Nestle, O. Graciela Scharovsky, Onishi, Ormandy, Pablo Matar, Proietti, Putzer, Rabinovich, Sakaguchi, Sangro, Shapira, Spaapen, Suzuki, Takahashi, Tang, Thornton, Trinchieri, Vignali, Yokoyama, Zou, Zou, Zwirner   +69 more
core   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Immunosuppression by Splenectomy and Lymph-node Irradiation [PDF]

, 1966
David L. Benninghoff
openalex   +1 more source