Results 161 to 170 of about 521,863 (391)

Serum-mediated immunosuppression in lung cancer [PDF]

, 1979
Armando E. Giuliano, Decio M. Rangel, Sidney H. Golub, E. Carmack Holmes, Donald L. Morton   +4 more
openalex   +1 more source

The current status of hepatic transplantation at the University of Pittsburgh. [PDF]

, 1995
Tacrolimus is a more potent and satisfactory immunosuppressant than CyA for combination therapy with prednisone. In randomized trials comparing the 2 drugs, the ability of tacrolimus to rescue intractably rejecting grafts on the competing CyA arm allowed
Abu-Elmagd, K, Demetris, J, Fontes, P, Fung, J, Furukawa, H, Mazariegos, G, McMichael, J, Rao, A, Reyes, J, Todo, S   +9 more
core  

Regulation of soluble CD127 protein release and corresponding transcripts expression in T lymphocytes from septic shock patients

Intensive Care Medicine Experimental, 2019
Julie Mouillaux, Camille Allam, Thomas Rimmelé, Thomas Uberti, Benjamin Delwarde, Julien Textoris, Guillaume Monneret, Estelle Peronnet, Fabienne Venet   +8 more
doaj   +1 more source

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

Effect of immunosuppression on the genetic resistance of A2G mice to neurovirulent influenza virus [PDF]

, 1975
Robert A. Fiske, Paul Klein
openalex   +3 more sources

PRIMARY MALIGNANCY IN PATIENTS UNDERGOING IMMUNOSUPPRESSION FOR RENAL TRANSPLANTATION

, 1969
Charles F. McKhann
openalex   +1 more source

The Induction and Abolition of Specific Immunosuppression of Heart Allografts in Rats by Use of Donor Blood and Cyclophosphamide [PDF]

, 1975
Richard L. Marquet, GERARD A. HEYSTEK
openalex   +1 more source

Temporary withdrawal of immunosuppression for life-threatening infections after liver transplantation [PDF]

, 1994
Bonet, H, Fung, JJ, Gonzalez-Pinto, I, Kramer, D, Kusne, S, Linden, P, Manez, R, Starzl, TE   +7 more
core   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source