Results 181 to 190 of about 458,490 (361)

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

BEAT-BK: An Adaptive, Randomized Controlled Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Kidney-pancreas Transplantation Recipients (BEAT-BK) Study Protocol. [PDF]

Transplant Direct
Gately R, Dymock M, Sabanayagam D, Campbell SB, Craig JC, Dharnidharka V, Francis A, Gleadle JM, Hajek M, Hamilton S, Howell M, Isbel N, Jaure A, Johnson DW, Kanellis J, Keung K, Kim S, Kok J, Kuypers DR, Larkins N, Lim WH, Mainra R, Marsh JA, Mihala G, Nankivell BJ, Ng S, Pilmore H, Scholes-Roberton N, Snelling T, Teixeira-Pinto A, Valks A, Yong K, Hawley C, Wong G.   +33 more
europepmc   +1 more source

Immunosuppression as a trigger for hyperinflammatory syndrome due to Strongyloides stercolaris in membranous nephropathy

, 2020
Mayra Ortega-Díaz, Marta Carretero, Juan A. Martín Navarro, Teresa Aramendi Sánchez, Roberto Alcázar Arroyo, Elena Prats, Patricia de Sequera Ortiz, Marta Albalate Ramón, Maria Teresa Jaldo Rodríguez, Laura Medina Zahonero   +9 more
openalex   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Combination antifibrotic and immunosuppressive therapy in progressive fibrosing ILD. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Fischer R, Abdul Rehman K.
europepmc   +1 more source

The connected past and future of transplantation, with particular emphasis on the liver [PDF]

, 2004
Starzl, TE
core  

Induction of Disseminated Virulent Cytomegalovirus Infection by Immunosuppression of Naturally Chronically Infected Wild Mice [PDF]

, 1974
Murray B. Gardner, J. Earle Officer, John C. Parker, John D. Estes, Robert W. Rongey   +4 more
openalex   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Editorial: Post-transplant haematological disorders in solid organ transplantation. [PDF]

Front Immunol
Ippoliti G.
europepmc   +1 more source

Comment: Newly Diagnosed Glomerulonephritis During COVID-19 Infection Undergoing Immunosuppression Therapy, a Case Report.

, 2020
Muhammed Mubarak, Ramin Tolouian, Jolanta Kowalewska, Hamid Nasri   +3 more
openalex   +1 more source