Results 191 to 200 of about 514,735 (343)

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

Advanced Science, EarlyView.
We show that intratumoral release of an immunotherapy—CpG —can be tuned with molecular precision by complexing it to an elastin‐like polypeptide (ELP). Injecting ELP‐CpG and an excipient ELP into tumors drives thermally‐triggered phase separation into a micro‐scale “sponge” depot that releases CpG at rates depending on the ELP composition, which ...
Joshua J. Milligan, Rachel L. Strader, Arunangshu Chakrabarty, Max Ney, Parul Sirohi, Jonathan C. Su, Anastasia K. Varanko, Yulia Shmidov, Kalina Tsolova, Cassio Mendes Fontes, Anna Finkelstein, Rohinee Mattikalli, Yun‐Xing Wang, Lixin Fan, Xinghai Li, Smita K. Nair, Ashutosh Chilkoti   +16 more
wiley   +1 more source

Immunosuppressant management in palliative care: a systematic review. [PDF]

BMC Palliat Care
Birchler KM, Hertler C, Pfrunder T, Blum D, Schettle M.   +4 more
europepmc   +1 more source

Specific and Non-Specific Immunosuppression in Chickens [PDF]

, 1975
P. Thaxton, Patricia S. Young
openalex   +1 more source

Differential survival of hamster-to-rat liver and cardiac xenografts under FK 506 immunosuppression [PDF]

, 1991
Demetris, AJ, Fung, JJ, Starzl, TE, Valdivia, LA   +3 more
core  

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

Immunosuppression in rabbits: skin and kidney allografts [PDF]

, 1975
C. J. Green
openalex   +1 more source

Weaning of immunosuppression in long-term recipients of living related renal transplants: A preliminary study [PDF]

, 1995
Fung, JJ, Mazariegos, GV, Ramos, H, Shapiro, R, Starzl, TE, Zeevi, A   +5 more
core  

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Immunosuppression in relation to organ transplantation.

, 1967
M. F. A. Woodruff
openalex  

Intra-Epithelial Carcinoma of the Vagina following Immunosuppression Treated with Topical 5-Fluorouracil [PDF]

, 1974
Peter Bowen‐Simpkins, M.G.R. Hull
openalex   +1 more source