Results 191 to 200 of about 556,132 (392)

Belatacept-versus Cyclosporine-Based Immunosuppression in Renal Transplant Recipients with Pre-existing Diabetes

, 2011
Lionel Rostaing, H. H. Neumayer, Rafael Reyes‐Acevedo, Barbara A. Bresnahan, Sander Florman, Š Vı́tko, Michael Heifets, Jun Xing, Dolca Thomas, Flavio Vincenti   +9 more
openalex   +2 more sources

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Immunosuppression as a trigger for hyperinflammatory syndrome due to Strongyloides stercolaris in membranous nephropathy

, 2020
Mayra Ortega-Díaz, Marta Carretero, Juan A. Martín Navarro, Teresa Aramendi Sánchez, Roberto Alcázar Arroyo, Elena Prats, Patricia de Sequera Ortiz, Marta Albalate Ramón, Maria Teresa Jaldo Rodríguez, Laura Medina Zahonero   +9 more
openalex   +1 more source

Human Glioma-Induced Immunosuppression Involves Soluble Factor(s) That Alters Monocyte Cytokine Profile and Surface Markers [PDF]

, 1999
Jian-Ping Zou, Lorri A. Morford, Claire Chougnet, Amy R. Dix, Andrëw G. Brööks, Naomi Torres, Jon D. Shuman, John E. Coligan, William H. Brooks, Thomas L. Roszman, Gene M. Shearer   +10 more
openalex   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

Advanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang, Mei Luo, Yuan Liu, Jingwen Yang, Yamei Chen, Chengxuan Chen, Lifei Ma, Stephanie Ding, James Wengler, Yong Zang, Bora Lim, Wenbo Li, Liuqing Yang, Chunru Lin, Lixia Diao, Leng Han   +15 more
wiley   +1 more source

Effects of Interferon-.ALPHA.(IFN-.ALPHA.) as an Immunological Modifier on Post-Surgical Cell Mediated Immunosuppression in Dogs.

, 1994
Youko NAKADA, Hisako EZAKI, Shigeo Tanaka, Toshifumi Kosaka, Masato KUWABARA, Fusaoki KOIDE   +5 more
openalex   +2 more sources

Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

Nature reviews. Immunology, 2013
R. Hotchkiss, G. Monneret, D. Payen
semanticscholar   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Immunosuppression and cancer. [PDF]

, 1973
Penn, I, Starzl, TE
core