Results 231 to 240 of about 392,479 (342)

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Care of the immunocompromised cancer patient in the perioperative period: Narrative review. [PDF]

Indian J Anaesth
Dabo-Trubelja A, Gottumukkala V.
europepmc   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

Chagas disease and immunosuppression

Memorias do Instituto Oswaldo Cruz, 1999
Marcelo Simão Ferreira
doaj   +1 more source

Invasive phaeohyphomycosis due to Parathyridaria percutanea in a liver transplant recipient. [PDF]

BMC Infect Dis
Obana A, Akabane M, Ohashi Y, Bagrodia N, Schenk A, Black S, Washburn K, Wiederhold NP, Cañete-Gibas CF, Meniru J, Nichols C, Sarwar S, Marschalk N.   +12 more
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Enhancing survival prediction for COVID-19 in diabetic patients in Mexico: integrating RMST, propensity score matching, and ensemble machine learning. [PDF]

Front Endocrinol (Lausanne)
Vargas-Santiago M, León-Velasco DA, Monroy R, Quezada-García S.   +3 more
europepmc   +1 more source

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia

New England Journal of Medicine, 2017
D. Townsley, P. Scheinberg, T. Winkler, R. Desmond, B. Dumitriu, O. Rios, B. Weinstein, Janet Valdez, J. Lotter, Xingmin Feng, M. Desierto, Harshraj Leuva, M. Bevans, Colin O. Wu, A. Larochelle, K. Calvo, C. Dunbar, N. Young   +17 more
semanticscholar   +1 more source

Assessment of the Degree of Immunosuppression Measured by Residual Expression of Genes Regulated by T-Cell Nuclear Factor (NFAT-RGE) in Lung Transplant Recipients [PDF]

M. Boada Pérez, Victoria Ruiz, Marta Erro, Piedad Ussetti, Silvia Rosado, Raquel Castejón, Martin Aguilar, Eva Revilla‐López, C. Bravo Masgoret, B. Saez Gimenez, Moises Zapata, Cristina Berastegui, Manuel López‐Meseguer, Yolanda Villena-Ortiz, J. Vima Bofarull, Vı́ctor Monforte, S. Gomez   +16 more
openalex   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source