Results 221 to 230 of about 282,999 (266)
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Trends in Pharmacological Sciences, 1993
Experimental models of autoimmune diseases have demonstrated that such disease can be prevented or treated by selectively interfering with activation of any of these cell types: antigen-presenting cells, autoreactive T cells and regulatory T cells. Luciano Adorini and colleagues discuss these approaches to selective immunosuppression and examine how ...
L, Adorini +3 more
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Experimental models of autoimmune diseases have demonstrated that such disease can be prevented or treated by selectively interfering with activation of any of these cell types: antigen-presenting cells, autoreactive T cells and regulatory T cells. Luciano Adorini and colleagues discuss these approaches to selective immunosuppression and examine how ...
L, Adorini +3 more
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Immunosuppression on the Horizon
Heart Failure Clinics, 2007Many novel immunosuppressive agents are under active clinical investigation. In addition, creative approaches are being developed for the use of established immunosuppressive agents, with the goal of minimizing immunosuppression as early as possible posttransplantation.
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Mechanisms of immunosuppression
Veterinary Immunology and Immunopathology, 1991Immunosuppresive disease is a major economic concern in domestic poultry production. Although many immunosuppressive agents have been described, mechanisms of how infectious and noninfectious agents compromise the immune system are poorly understood in avian species. Two categories, generalized and antigen-specific immunosuppression have been described
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[Pharmacogenetics of immunosuppressants].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015Individualized drug therapy with immunosuppressants is an hot topic in transplantation. Therapeutic drug monitoring (TDM) is currently utilized to guide therapy, but toxic or subtherapeutic concentrations can only be identified after the drug is administered.
Cojutti P. G., Baraldo M.
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Surgical Clinics of North America, 1999
Although several new immunosuppressive medications have been developed in the past decade, many possible avenues are yet to be explored. Although the newer agents have not reflected any clear benefit in patient or graft survival over CsA or tacrolimus, they have been useful in reducing the incidence and severity of rejection, reducing the concomitant ...
A, Jain +4 more
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Although several new immunosuppressive medications have been developed in the past decade, many possible avenues are yet to be explored. Although the newer agents have not reflected any clear benefit in patient or graft survival over CsA or tacrolimus, they have been useful in reducing the incidence and severity of rejection, reducing the concomitant ...
A, Jain +4 more
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Current Pharmaceutical Design, 2008
The often fatal sepsis syndrome is characterized by the systemic release of inflammatory mediators, which is regulated and counterbalanced by the coordinated expression of anti-inflammatory molecules. The magnitude of sepsis-induced tissue injury and subsequent risk of infectious complications is dictated by the balance between the expression of pro ...
Kenneth, Lyn-Kew, Theodore J, Standiford
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The often fatal sepsis syndrome is characterized by the systemic release of inflammatory mediators, which is regulated and counterbalanced by the coordinated expression of anti-inflammatory molecules. The magnitude of sepsis-induced tissue injury and subsequent risk of infectious complications is dictated by the balance between the expression of pro ...
Kenneth, Lyn-Kew, Theodore J, Standiford
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Immunosuppressive Cyclolignans
Journal of Medicinal Chemistry, 1996The immunosuppressive activity of several lactonic, nonlactonic, and heterocycle-fused cyclolignans has been demonstrated for the first time by use of a T-cell-mediated immune response. Of the compounds tested, 4'-demethyldeoxypodophyllotoxin (8), beta-apopicropodophyllin (6), and the isoxazoline-fused cyclolignan 15 are the most potent with respect to
M, Gordaliza +5 more
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Ophthalmology Clinics of North America, 2002
The treatment of ocular inflammatory disease continues to be a major challenge as the clinician tries to balance the risks and the benefits of immunosuppressive therapy. Currently, corticosteroids, antimetabolites, and calcineurin inhibitors are the most commonly used agents.
Ali R, Djalilian, Robert B, Nussenblatt
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The treatment of ocular inflammatory disease continues to be a major challenge as the clinician tries to balance the risks and the benefits of immunosuppressive therapy. Currently, corticosteroids, antimetabolites, and calcineurin inhibitors are the most commonly used agents.
Ali R, Djalilian, Robert B, Nussenblatt
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