Results 291 to 300 of about 353,556 (317)

PTCy unchained in matched siblings: the D is silent in GVHD. [PDF]

Blood Adv
Gagelmann N, Vatsayan A.
europepmc   +1 more source

Engineered brain‐targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma

Exploration, EarlyView.
An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang, Yong Li, Shaoping Jiang, Yuxin Tian, Mengjie Zhang, Shuai Guo, Pengfei Wu, Jianan Li, Lin Xu, Wenpei Li, Yushu Wang, Huile Gao, Yuanyu Huang, Yuhua Weng, Shaobo Ruan   +14 more
wiley   +1 more source

CD154 blockade effectively controls antibody-mediated rejection in highly sensitized nonhuman primate kidney transplant recipients. [PDF]

Sci Transl Med
Anwar IJ, DeLaura I, Ladowski JM, Schilirò D, Gao Q, Manook M, Yoon J, Belloni R, Park A, Schuster DJ, Song M, Lin L, Farris AB, Magnani D, Williams K, Kwun J, Knechtle SJ.   +16 more
europepmc   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

Exploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng, Ao Hua, Shiyou Li, Zhijie Zhang, Xiang Chen, Qiang Wang, Xing Wang, Zhiqin Chu, Xiangliang Yang, Zifu Li   +9 more
wiley   +1 more source

Sub-Immunosuppressive Tacrolimus Ameliorates Amyloid-Beta and Tau Pathology in 3xTg-AD Mice. [PDF]

Int J Mol Sci
Silva J, Tumurbaatar B, Guptarak J, Zhang WR, Fracassi A, Taglialatela G.   +5 more
europepmc   +1 more source

Surface‐Anchored Ticagrelor Gelatin Nanoparticles‐Platelets System for Enhanced Anti‐PD‐L1 Therapy Response and Boosted Chemotherapeutic Efficacy of Nanomedicines

Exploration, EarlyView.
Ticagrelor nanoparticles modified platelets could adhere to tumor‐associated platelets by specific recruiting ability and responsively release ticagrelor under MMPs stimulation. The released ticagrelor could inhibit platelets activity, enhancing tumor treatment efficacy.
Qi Lu, Hao Ye, Jian Zhao, Xiaoyuan Fan, Kaiyuan Wang, Zeyu Han, Tian Liu, Lili Du, Jiaxuan Song, Helin Wang, Haotian Zhang, Zhonggui He, Jin Sun   +12 more
wiley   +1 more source

Navigating Epstein-Barr Virus (EBV) and Post-Transplant Lymphoproliferative Disorder (PTLD) in Pediatric Liver Transplantation: Current Knowledge and Strategies for Treatment and Surveillance. [PDF]

Viruses
Chen EY, Dilwali N, Mysore KR, Hassan S, Smith SK, Karnsakul W.   +5 more
europepmc   +1 more source

Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model. [PDF]

NPJ Regen Med
Chen HC, Cheng YC, Hsieh ML, Lin PJ, Wissel EF, Steward T, Chang CMC, Coonen J, Hacker TA, Kamp TJ, Hsieh PCH.   +10 more
europepmc   +1 more source

Ten‐year follow‐up of a case of eosinophilic granulomatous with polyangiitis

ESC Heart Failure, EarlyView.
Jiange Qiao, Mingjie Cao, Tao Ren, Chen Gong, Zhijun Jie, Qingmin Yang, Jindong Shi   +6 more
wiley   +1 more source

Disseminated Chickenpox Following Live Varicella Vaccination in a Crohn's Disease Patient on Combination Immunosuppression. [PDF]

Case Rep Gastrointest Med
Solano Q, Uttal S, Higgins PDR, Berinstein JA.   +3 more
europepmc   +1 more source