Results 301 to 310 of about 514,735 (343)
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ACS Nano, 2021
The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell ablation efficiency has received extensive interest in oncotherapy.
Na Tao +9 more
semanticscholar +1 more source
The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell ablation efficiency has received extensive interest in oncotherapy.
Na Tao +9 more
semanticscholar +1 more source
Psychosomatics, 2002
This edition of the Med-Psych Drug-Drug Interactions Update begins a change in format. Starting with this column, each column will feature one drug-drug interaction (DDI) topic that will be explored in depth. This edition features DDIs associated with the commonly used immunosuppressants.
Scott C, Armstrong +2 more
openaire +2 more sources
This edition of the Med-Psych Drug-Drug Interactions Update begins a change in format. Starting with this column, each column will feature one drug-drug interaction (DDI) topic that will be explored in depth. This edition features DDIs associated with the commonly used immunosuppressants.
Scott C, Armstrong +2 more
openaire +2 more sources
Psychosomatics, 2004
Immunosuppressants are prescribed to prevent rejection of transplanted tissues and organs and are also used in the treatment of autoimmune disorders. Consultation-liaison psychiatrists increasingly encounter patients taking these agents as the number of transplant recipients increases and the indications for the use of immunosuppressants expands. These
Marian, Fireman +3 more
openaire +2 more sources
Immunosuppressants are prescribed to prevent rejection of transplanted tissues and organs and are also used in the treatment of autoimmune disorders. Consultation-liaison psychiatrists increasingly encounter patients taking these agents as the number of transplant recipients increases and the indications for the use of immunosuppressants expands. These
Marian, Fireman +3 more
openaire +2 more sources
Gastroenterology Clinics of North America, 1992
The role and pharmacology of a variety of immunosuppressant agents in the gastrointestinal tract and liver are reviewed in this article. Immunosuppressants covered include cyclosporine, corticosteroids, OKT3, antithymocyte globulin, azathioprine, methotrexate, and FK506. Guidelines for the use and complications of immunosuppressants in liver, pancreas,
J W, Marsh, K L, Vehe, H M, White
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The role and pharmacology of a variety of immunosuppressant agents in the gastrointestinal tract and liver are reviewed in this article. Immunosuppressants covered include cyclosporine, corticosteroids, OKT3, antithymocyte globulin, azathioprine, methotrexate, and FK506. Guidelines for the use and complications of immunosuppressants in liver, pancreas,
J W, Marsh, K L, Vehe, H M, White
openaire +2 more sources
Immunosuppression by Discodermolide
Annals of the New York Academy of Sciences, 1993In summary, discodermolide, a novel, marine-derived compound, is a potent in vitro and in vivo immunosuppressive agent. Discodermolide blocks cellular proliferation in lymphoid and nonlymphoid cells. This blocking action is not due to cytotoxicity. Blockage of cell proliferation by discodermolide appears to occur at the G2/M interface of the cell cycle,
Longley, R. E. +4 more
openaire +3 more sources
Clinical Pharmacology & Therapeutics, 1974
In this paper, I propose to review some of the current concepts of development of immunocompetence, to describe the cellular events that follow exposure to antigen, and to show how these data may be applied to therapy with immunosuppressive drugs. The greatest emphasis will be placed on the glucocorticoids, because these agents are widely employed in ...
openaire +2 more sources
In this paper, I propose to review some of the current concepts of development of immunocompetence, to describe the cellular events that follow exposure to antigen, and to show how these data may be applied to therapy with immunosuppressive drugs. The greatest emphasis will be placed on the glucocorticoids, because these agents are widely employed in ...
openaire +2 more sources
2013
A variety of immunosuppressants and disease-modifying anti-rheumatic drugs (DMARDs) with beneficial effects on inflammatory rheumatic diseases have been identified over the last 50 years. Their use for these conditions is now well established and has led to considerable improvements in disease management.
Joanna Ledingham, Sarah Westlake
openaire +1 more source
A variety of immunosuppressants and disease-modifying anti-rheumatic drugs (DMARDs) with beneficial effects on inflammatory rheumatic diseases have been identified over the last 50 years. Their use for these conditions is now well established and has led to considerable improvements in disease management.
Joanna Ledingham, Sarah Westlake
openaire +1 more source
Trends in Pharmacological Sciences, 1993
Experimental models of autoimmune diseases have demonstrated that such disease can be prevented or treated by selectively interfering with activation of any of these cell types: antigen-presenting cells, autoreactive T cells and regulatory T cells. Luciano Adorini and colleagues discuss these approaches to selective immunosuppression and examine how ...
L, Adorini +3 more
openaire +3 more sources
Experimental models of autoimmune diseases have demonstrated that such disease can be prevented or treated by selectively interfering with activation of any of these cell types: antigen-presenting cells, autoreactive T cells and regulatory T cells. Luciano Adorini and colleagues discuss these approaches to selective immunosuppression and examine how ...
L, Adorini +3 more
openaire +3 more sources
Immunosuppression for Myocarditis
New England Journal of Medicine, 1995The diagnosis of acute myocarditis has been a conundrum. One criterion is the clinical picture of the sudden onset of cardiac failure and arrhythmias, often associated with a febrile illness; the other criterion is a myocardial-biopsy specimen that shows a specified degree of myocyte damage and infiltration by T lymphocytes.
William J. McKenna, Michael J. Davies
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Frontiers in Immunosuppression
Transplantation Proceedings, 2008Immunosuppressive therapy has relied on tailoring combinations of relatively nonselective drugs to individual patient tolerance. The next steps in the development of small molecule agents are to define and to develop selective inhibitors of cascades unique to T cells.
openaire +5 more sources